QuickView for SPTLC1;jsessionid=20FBE4840BC175A90D7789FAEE71BD1F;jsessionid=1DA8D782EAEAC9BB499968958EA1779B;jsessionid=9C037B5D47827EC546144692C2F8A5A0 (gene)
- Gene Symbol:
- LCB1
Saccharomyces cerevisiae - Full name:
- Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
- Synonyms:
- END8, LCB1, lcb1, Lcb1, LCB1, TSC2, YMR296C
- Genomic Location:
- Chr XIII: 859214-860890
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | transferase activity, transferring acyl groups other than amino-acyl groups | vitamin binding | coenzyme binding | pyridoxal phosphate binding | catalytic activity | transferase activity, transferring acyl groups | anion binding | palmitoyltransferase activity | ion binding | organic cyclic compound binding | vitamin B6 binding | transferase activity | serine C-palmitoyltransferase activity | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
cellular process | sphingolipid metabolic process | cellular lipid metabolic process | sphingolipid biosynthetic process | cellular biosynthetic process | nitrogen compound metabolic process | lipid metabolic process | biosynthetic process | lipid biosynthetic process | metabolic process | membrane lipid metabolic process | organic substance metabolic process | cellular metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | catalytic complex | cell | palmitoyltransferase complex | intrinsic component of membrane | cytoplasm | intracellular organelle | SPOTS complex | endoplasmic reticulum | serine C-palmitoyltransferase complex | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | transferase complex | endoplasmic reticulum palmitoyltransferase complex | membrane-bounded organelle | organelle | intracellular | membrane
