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QuickView for SRY;jsessionid=FF06E6AA0C5D668528FC607D8D79625A;jsessionid=96828A5FDB359563E5A0A39503C0D252 (gene)


Gene Symbol:
Sry Rattus norvegicus Rattus norvegicus
Full name:
sex determining region Y
Synonyms:
SRYGENE, Sry1, Sry3BI, Tdf, Tdy, sex-determining region Y protein, HMG box transcription factor Sry1, HMG box transcription factor Sry3BI, Testis determining locus, sex determining region of Chr Y, sex determining region on Y, testis-determining factor
Genomic Location:
N/A
Description:
transcriptional activator; involved in male sex determination
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Pan troglodytes
External Links:
Entrez Gene


Transcripts Names
NM_012772
Protein Names
Q9ERV8



GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enzyme binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | DNA binding | protein heterodimerization activity | organic cyclic compound binding | DNA binding, bending | protein binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | calmodulin binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | male sex determination | developmental process involved in reproduction | gonad development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | positive regulation of gonad development | positive regulation of cellular biosynthetic process | cellular process | reproductive system development | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | development of primary sexual characteristics | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | regulation of gene expression | positive regulation of male gonad development | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | regulation of male gonad development | aromatic compound biosynthetic process | sex determination | regulation of cellular metabolic process | regulation of RNA metabolic process | development of primary male sexual characteristics | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | male sex differentiation | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | male gonad development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | reproductive structure development | regulation of developmental process | developmental process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | sex differentiation | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular