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QuickView for STEAP;jsessionid=3820554E5CC1FFE16E0469455680361E;jsessionid=5CC5820CBB25F9B08106FFA3201520E4 (gene)


Gene Symbol:
STEAP1 Homo sapiens Homo sapiens
Full name:
STEAP family member 1
Synonyms:
PRSS24, STEAP, metalloreductase STEAP1, STEAP1 metalloreductase, six transmembrane epithelial antigen of the prostate 1, six-transmembrane epithelial antigen of prostate 1
Genomic Location:
Chr 7: 89621625-89632077
Description:
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 7
7q21.13


Transcripts Names
NM_012449
XM_001131341
Protein Names
O95034
A4D1E0
Q9UHE8



GO Molecular Function

cation binding | passive transmembrane transporter activity | transmembrane transporter activity | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor | oxidoreductase activity, oxidizing metal ions | catalytic activity | ferric-chelate reductase (NADPH) activity | transporter activity | ion binding | channel activity | cupric reductase activity | metal ion binding | oxidoreductase activity

GO Biological Process

iron ion transmembrane transport | establishment of localization | ferric iron import across plasma membrane | localization | passive transmembrane transporter activity | metal ion transport | transition metal ion transport | iron ion import | transmembrane transporter activity | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor | oxidoreductase activity, oxidizing metal ions | metal ion homeostasis | ferric-chelate reductase (NADPH) activity | ion transmembrane transport | cation homeostasis | ferric iron transport | homeostatic process | iron ion homeostasis | cation transmembrane transport | iron ion import across plasma membrane | import into cell | copper ion import | metabolic process | oxidation-reduction process | chemical homeostasis | ferric iron import | copper ion transport | ion homeostasis | inorganic cation transmembrane transport | transmembrane transport | cation transport | channel activity | iron ion transport | inorganic cation import across plasma membrane | cupric reductase activity | ion transport | transition metal ion homeostasis | oxidoreductase activity

GO Cellular Component

integral component of membrane | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | cell-cell junction | endosome membrane | endomembrane system | plasma membrane | vesicle | integral component of plasma membrane | endosome | membrane-bounded organelle | organelle | cell periphery | intracellular vesicle | intracellular | cell junction | membrane | intrinsic component of plasma membrane