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QuickView for STXBP2;jsessionid=6A2F860C0AF7E76917126C1637AED0D3;jsessionid=28811BBBE4FE655BF9A5D9956FC6B353;jsessionid=21E3E40A90CA0EE8032000F5C5DE21BA (gene)


Gene Symbol:
Stxbp2 Rattus norvegicus Rattus norvegicus
Full name:
syntaxin binding protein 2
Synonyms:
Munc18b, syntaxin-binding protein 2, munc18-2, protein unc-18 homolog 2, protein unc-18 homolog B, syntaxin binding protein Munc18-2, unc-18 homolog 2, unc-18 homolog B, unc-18B, unc18-2
Genomic Location:
Chr 12: 2511793-2522818
Description:
syntaxin binding protein; important for synaptic vesicle exoctyosis; may be a component of the SNARE complex; may be involved with pancreatic beta-cell exocytosis
Orthologs:
Homo sapiens Mus musculus Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Canis lupus familiaris Danio rerio Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_031126
XR_595188
XM_006248783
Protein Names
Q62753



GO Molecular Function

syntaxin binding | protein binding | syntaxin-3 binding | SNARE binding | syntaxin-1 binding

GO Biological Process

positive regulation of immune response | synaptic vesicle exocytosis | response to acidic pH | exocytosis | response to cytokine | neurotransmitter secretion | neutrophil activation | regulation of cellular localization | regulation of localization | establishment of localization | regulation of immune system process | defense response | intracellular transport | cellular process | secretion | leukocyte degranulation | establishment of organelle localization | localization | protein transport | positive regulation of immune effector process | chemical synaptic transmission | macromolecule localization | membrane docking | establishment of localization in cell | regulation of immune response | regulation of cellular process | leukocyte activation | organelle localization | regulation of mast cell degranulation | cellular response to interferon-gamma | response to stimulus | neutrophil degranulation | positive regulation of immune system process | response to stress | leukocyte activation involved in immune response | positive regulation of mast cell degranulation | positive regulation of cell activation | cellular localization | secretion by cell | response to pH | cell-cell signaling | regulation of intracellular transport | positive regulation of exocytosis | regulation of neurotransmitter levels | synaptic vesicle cycle | leukocyte mediated immunity | cell killing | positive regulation of secretion | organic substance transport | synaptic signaling | regulation of mast cell activation | peptide transport | vesicle-mediated transport | cellular response to cytokine stimulus | establishment of vesicle localization | regulated exocytosis | positive regulation of regulated secretory pathway | cell communication | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | positive regulation of transport | response to organic substance | regulation of exocytosis | positive regulation of leukocyte activation | amide transport | regulation of vesicle-mediated transport | calcium ion regulated exocytosis | regulation of secretion | immune response | leukocyte mediated cytotoxicity | positive regulation of mast cell activation | regulation of cell activation | vesicle docking | establishment of protein localization | response to interferon-gamma | regulation of regulated secretory pathway | positive regulation of intracellular transport | cell activation | signaling | synaptic vesicle localization | protein localization | vesicle docking involved in exocytosis | regulation of transport | innate immune response | neurotransmitter transport | signal release | neutrophil mediated immunity | vesicle localization | immune system process | synaptic vesicle transport | cellular response to organic substance

GO Cellular Component

secretory granule | zymogen granule | intracellular membrane-bounded organelle | synapse | apical plasma membrane | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | lamellipodium | cytoplasm | intracellular organelle | secretory granule membrane | apical part of cell | presynapse | protein-containing complex | cell projection | secretory vesicle | endomembrane system | plasma membrane | cytolytic granule | cell leading edge | vacuole | vesicle | specific granule | lytic vacuole | SNARE complex | membrane-bounded organelle | organelle | vesicle membrane | zymogen granule membrane | lysosome | cell periphery | azurophil granule | cytosol | intracellular vesicle | endocytic vesicle | intracellular | membrane | cytoplasmic vesicle membrane | phagocytic vesicle