QuickView for SYNJ1;jsessionid=AFE1E8F9EB4021508B0AF5E22A851462;jsessionid=DEA11D303AE22C05DE6A01C95BCE75B9;jsessionid=0885FB14DFD9835775DD4CB0DC6C84E3;jsessionid=5165E81E1A09FF21A1132603D136E713 (gene)
- Gene Symbol:
- Synj1
Rattus norvegicus - Full name:
- synaptojanin 1
- Synonyms:
- synaptojanin-1, synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1
- Genomic Location:
- Chr 11: 30920857-30998783
- Description:
-
has inositol 5-phosphatase activity; interacts with dynamin to play a role in synaptic vesicle recycling
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-148 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-190 , Predicted Gene Targets for miR-200b , Predicted Gene Targets for miR-218 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-25
GO Molecular Function
phosphatidylinositol bisphosphate phosphatase activity | phosphatidylinositol-4-phosphate phosphatase activity | nucleic acid binding | protein-containing complex binding | SH3 domain binding | inositol phosphate phosphatase activity | phosphatase activity | hydrolase activity | phosphatidylinositol monophosphate phosphatase activity | catalytic activity | protein domain specific binding | hydrolase activity, acting on ester bonds | inositol trisphosphate phosphatase activity | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | phosphatidylinositol phosphate phosphatase activity | phosphatidylinositol phosphate 5-phosphatase activity | organic cyclic compound binding | phosphatidylinositol-4,5-bisphosphate phosphatase activity | EH domain binding | protein binding | phosphatidylinositol-3-phosphatase activity | phosphoric ester hydrolase activity | phosphatidylinositol phosphate 4-phosphatase activity | heterocyclic compound binding | inositol-1,4,5-trisphosphate 5-phosphatase activity | protein C-terminus binding | RNA binding
GO Biological Process
synaptic vesicle exocytosis | phosphatidylinositol bisphosphate phosphatase activity | brain development | exocytosis | response to cytokine | positive regulation of cellular component organization | regulation of neurogenesis | neurotransmitter secretion | regulation of cell development | regulation of localization | phosphatidylinositol metabolic process | establishment of localization | neurotransmitter receptor internalization | positive regulation of developmental process | cell differentiation | nervous system development | organophosphate catabolic process | neurogenesis | polyol metabolic process | regulation of organelle organization | generation of neurons | phosphatidylinositol-4-phosphate phosphatase activity | phospholipid metabolic process | intracellular transport | cellular process | secretion | organic substance catabolic process | establishment of organelle localization | localization | chemical synaptic transmission | learning | establishment of localization in cell | regulation of cell differentiation | inositol phosphate catabolic process | regulation of cellular process | catabolic process | organelle localization | phosphorylated carbohydrate dephosphorylation | inositol phosphate phosphatase activity | cellular component organization | cellular lipid metabolic process | phosphatase activity | head development | response to stimulus | alcohol metabolic process | phosphatidylinositol monophosphate phosphatase activity | cellular localization | secretion by cell | positive regulation of gliogenesis | cellular component assembly | cell-cell signaling | regulation of neurotransmitter levels | organic hydroxy compound metabolic process | synaptic vesicle cycle | system development | alcohol catabolic process | positive regulation of organelle organization | multicellular organism development | phosphorus metabolic process | learning or memory | lipid metabolic process | localization within membrane | synaptic vesicle recycling | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | response to lipid | nervous system process | synaptic signaling | organophosphate metabolic process | synaptic vesicle priming | small molecule metabolic process | cellular carbohydrate metabolic process | vesicle-mediated transport | positive regulation of cell differentiation | cognition | establishment of vesicle localization | inositol trisphosphate phosphatase activity | inositol phosphate dephosphorylation | positive regulation of endosome organization | regulated exocytosis | cellular protein-containing complex assembly | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | carbohydrate metabolic process | phosphatidylinositol phosphate phosphatase activity | phosphatidylinositol phosphate 5-phosphatase activity | phosphate-containing compound metabolic process | cell communication | receptor internalization | synaptic vesicle endocytosis | phosphatidylinositol-4,5-bisphosphate phosphatase activity | protein-containing complex localization | lipid modification | cellular protein complex disassembly | glycerolipid metabolic process | positive regulation of transport | response to retinoic acid | vesicle uncoating | postsynaptic neurotransmitter receptor internalization | protein-containing complex assembly | response to organic substance | phosphatidylinositol dephosphorylation | import into cell | phosphatidylinositol-3-phosphatase activity | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | regulation of vesicle-mediated transport | calcium ion regulated exocytosis | endocytosis | behavior | organic substance metabolic process | animal organ development | regulation of endosome organization | protein depolymerization | synaptic vesicle uncoating | dephosphorylation | regulation of gliogenesis | signaling | phosphatidylinositol phosphate 4-phosphatase activity | regulation of endocytosis | synaptic vesicle localization | protein-containing complex disassembly | regulation of nervous system development | regulation of developmental process | receptor-mediated endocytosis | glycerophospholipid metabolic process | developmental process | regulation of transport | neurotransmitter transport | receptor metabolic process | signal release | central nervous system development | vesicle localization | clathrin coat disassembly | phospholipid dephosphorylation | cellular metabolic process | synaptic vesicle transport | inositol-1,4,5-trisphosphate 5-phosphatase activity | positive regulation of endocytosis | regulation of cellular component organization | inositol phosphate metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
supramolecular fiber | synapse | neuron projection | organelle membrane | clathrin coat of coated pit | cell | plasma membrane protein complex | distal axon | synaptic membrane | terminal bouton | microtubule | cytoplasm | intracellular organelle | presynapse | protein-containing complex | cell projection | endomembrane system | plasma membrane | vesicle | perinuclear region of cytoplasm | clathrin-coated pit | microtubule cytoskeleton | membrane-bounded organelle | clathrin coat | organelle | vesicle membrane | axon terminus | cell periphery | axon | neuron projection terminus | cytoskeleton | intracellular | membrane | supramolecular complex | membrane coat
