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QuickView for Slc26a3;jsessionid=E57BA0419623D018890FB4AB5A5F8992;jsessionid=589A6272071E8ED7AE65896FB79EE7B4 (gene)


Gene Symbol:
Slc26a3 Mus musculus Mus musculus
Full name:
solute carrier family 26, member 3
Synonyms:
9030623B18Rik, 9130013M11Rik, AV376035, Dra, chloride anion exchanger, down-regulated in adenoma
Genomic Location:
Chr 12: 32123166-32158584
Description:
This gene encodes a member of the solute carrier/sulfate transporter family. The encoded protein is predominantly expressed in the intestine where it is essential for chloride absorption. Disruption of this gene results in chloride-rich diarrhea and compensatory up-regulation of ion-absorbing transporters.
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_021353
XM_017314950
XM_011243812
Protein Names
B2RTD9
Q9WVC8



GO Molecular Function

organic anion transmembrane transporter activity | anion transmembrane transporter activity | dicarboxylic acid transmembrane transporter activity | transmembrane transporter activity | organic acid transmembrane transporter activity | inorganic anion transmembrane transporter activity | anion:anion antiporter activity | chloride transmembrane transporter activity | bicarbonate transmembrane transporter activity | secondary active sulfate transmembrane transporter activity | antiporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | carboxylic acid transmembrane transporter activity | protein binding | secondary active transmembrane transporter activity | sulfate transmembrane transporter activity | oxalate transmembrane transporter activity

GO Biological Process

developmental process involved in reproduction | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | cell differentiation | male gamete generation | cellular chemical homeostasis | response to organophosphorus | cellular process | dicarboxylic acid transmembrane transporter activity | localization | cellular homeostasis | sulfate transport | cell maturation | dicarboxylic acid transport | anion transport | multicellular organismal reproductive process | gamete generation | transmembrane transporter activity | cellular response to organonitrogen compound | chloride transmembrane transport | response to stimulus | sulfate transmembrane transport | germ cell development | chloride transport | organic acid transmembrane transporter activity | inorganic anion transport | reproduction | cellular response to organic cyclic compound | spermatid differentiation | inorganic anion transmembrane transporter activity | carboxylic acid transmembrane transport | anion:anion antiporter activity | regulation of membrane potential | response to nitrogen compound | reproductive process | chloride transmembrane transporter activity | response to purine-containing compound | membrane hyperpolarization | ion transmembrane transport | bicarbonate transmembrane transporter activity | secondary active sulfate transmembrane transporter activity | organic substance transport | cellular ion homeostasis | antiporter activity | active transmembrane transporter activity | organic acid transport | ion transmembrane transporter activity | bicarbonate transport | organic anion transport | oxalate transport | cation homeostasis | cellular cation homeostasis | regulation of intracellular pH | carboxylic acid transmembrane transporter activity | homeostatic process | multicellular organism reproduction | response to organic substance | regulation of pH | anion transmembrane transport | anatomical structure development | organic acid transmembrane transport | developmental maturation | chemical homeostasis | ion homeostasis | cellular response to cAMP | spermatid development | secondary active transmembrane transporter activity | regulation of cellular pH | response to cAMP | sulfate transmembrane transporter activity | oxalate transmembrane transporter activity | intracellular pH elevation | transmembrane transport | sperm capacitation | response to organic cyclic compound | cellular monovalent inorganic cation homeostasis | cell development | carboxylic acid transport | developmental process | spermatogenesis | response to organonitrogen compound | ion transport | cellular response to organic substance | sexual reproduction | multicellular organismal process

GO Cellular Component

sperm flagellum | brush border | integral component of membrane | sperm midpiece | apical plasma membrane | cell projection membrane | cell | intrinsic component of membrane | 9+2 motile cilium | motile cilium | brush border membrane | apical part of cell | cell projection | plasma membrane | cilium | integral component of plasma membrane | organelle | cell periphery | membrane | intrinsic component of plasma membrane