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QuickView for Sox2;jsessionid=5D6C787EF153F66DB750363068080036;jsessionid=721935673AC744A7418A9BE054B0EE34 (gene)


Gene Symbol:
SOX2 Gallus gallus Gallus gallus
Full name:
SRY (sex determining region Y)-box 2
Synonyms:
N/A
Genomic Location:
Chr 9: 17990071-17991429
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AACTTT_UNKNOWN MEF2_01 SOX5_01 GATA1_01 HFH1_01 HNF3B_01 ACTWSNACTNY_UNKNOWN LYF1_01 CEBP_01 SRY_02


Transcripts Names
NM_205188
Protein Names
P48430
Q54A48



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | miRNA binding | DNA binding | organic cyclic compound binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | brain development | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | regulation of neurogenesis | regulation of cell development | somatic stem cell population maintenance | regulation of programmed cell death | eye development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | cell fate specification | negative regulation of signaling | negative regulation of nucleic acid-templated transcription | stem cell population maintenance | regulation of proteolysis | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | diencephalon development | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | pituitary gland development | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | head development | response to stimulus | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | cellular nitrogen compound metabolic process | endodermal cell fate commitment | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | regulation of nucleic acid-templated transcription | formation of anatomical boundary | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of peptidase activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of phosphorylation | sensory organ boundary specification | regulation of neuron differentiation | regulation of gene expression | cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | cell fate determination involved in pattern specification | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | endoderm formation | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | endodermal cell fate specification | endocrine system development | sensory organ development | animal organ formation | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | inner ear development | regulation of protein phosphorylation | regulation of RNA metabolic process | cell fate commitment involved in pattern specification | embryonic morphogenesis | negative regulation of epithelial cell proliferation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regionalization | positive regulation of protein modification process | response to organic substance | gland development | cell cycle arrest | response to wounding | regulation of intracellular signal transduction | anatomical structure development | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | ear development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | negative regulation of neuron differentiation | gene expression | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | transcription, DNA-templated | positive regulation of MAPK cascade | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | regulation of cell communication | negative regulation of signal transduction | regulation of transcription, DNA-templated | regulation of epithelial cell proliferation | positive regulation of phosphorylation | endodermal cell differentiation | endoderm development | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule biosynthetic process | cell fate commitment involved in formation of primary germ layer | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | cell fate determination | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | ossification | osteoblast differentiation | gastrulation | cellular metabolic process | regulation of cell death | sensory organ precursor cell fate determination | negative regulation of cell development | negative regulation of cell differentiation | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular