QuickView for Sp3;jsessionid=ADC507B3557F2E4A6CDD17346C15FC46;jsessionid=515693D65F382546B61C45AD56DF6A0D (gene)

Gene Symbol:

Sp3 Mus musculus

Full name:

trans-acting transcription factor 3

Synonyms:

D130027J01Rik, transcription factor Sp3

Genomic Location:

Chr 2: 72774487-72819035

Description:

This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that...

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This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses transcription of numerous genes. Alternative splicing results in transcript variants encoding different isoforms, and one variant initiates translation from a non-AUG (AUA) codon.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ELK1_01 ,  E2F_02 ,  GATA1_01 ,  GATA2_01 ,  EVI1_04 ,  CEBPA_01 ,  PBX1_02 ,  AP2_Q6 ,  LMO2COM_02 ,  NFAT_Q6 ,  ETS2_B ,  E2F_Q4 ,  E2F_Q6 ,  E2F1_Q3 ,  E2F1_Q6 ,  AP2ALPHA_01 ,  MAF_Q6 ,  SP3_Q3 ,  GCGNNANTTCC_UNKNOWN ,  E2F1DP1_01 ,  E2F1DP2_01 ,  E2F4DP1_01 ,  E2F4DP2_01 ,  E2F1DP1RB_01 ,  GCTNWTTGK_UNKNOWN ,  SMAD_Q6 ,  SP1_Q2_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  ACTGAAA_MIR30A3P_MIR30E3P ,  GTATGAT_MIR154_MIR487 ,  AAGCCAT_MIR135A_MIR135B ,  TATTATA_MIR374 ,  TGTATGA_MIR4853P ,  GTATTAT_MIR3693P ,  KMCATNNWGGA_UNKNOWN ,  TTGCCAA_MIR182 ,  GTAAGAT_MIR200A ,  ATATGCA_MIR448 ,  AGCATTA_MIR155 ,  GCAAAAA_MIR129 ,  CTTTGTA_MIR524 ,  TTTGTAG_MIR520D ,  TGCCTTA_MIR124A ,  AACTGAC_MIR223 ,  GTGCAAA_MIR507 ,  ATGTACA_MIR493 ,  GCATTTG_MIR105 ,  GTTATAT_MIR410 ,  ATTCTTT_MIR186 ,  CGTCTTA_MIR208 ,  TGCAAAC_MIR452 ,  SMTTTTGT_UNKNOWN ,  TAANNYSGCG_UNKNOWN ,  TCCATTKW_UNKNOWN ,  RYTTCCTG_ETS2_B ,  GGGAGGRR_MAZ_Q6 ,  YTATTTTNR_MEF2_02 ,  CCCNNGGGAR_OLF1_01 ,  GGGCGGR_SP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-188 ,  Predicted Gene Targets for miR-363 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-505 ,  Predicted Gene Targets for miR-543

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