QuickView for Ste23p (gene)
- Gene Symbol:
- Ide
Rattus norvegicus - Full name:
- insulin degrading enzyme
- Synonyms:
- INSDEGM, insulin-degrading enzyme, insulin protease, insulinase, insulysin
- Genomic Location:
- Chr 1: 241547869-241646052
- Description:
-
enzyme involved in the degradation of bioactive peptides
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
metallopeptidase activity | peptide binding | peptide hormone binding | amyloid-beta binding | cation binding | metalloendopeptidase activity | neurotransmitter binding | ribonucleotide binding | insulin binding | nucleotide binding | signaling receptor binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | modification-dependent protein binding | nucleoside-triphosphatase activity | amide binding | purine nucleotide binding | identical protein binding | beta-endorphin binding | ion binding | organic cyclic compound binding | hormone binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | zinc ion binding | protein dimerization activity | hydrolase activity, acting on acid anhydrides | transition metal ion binding | purine ribonucleotide binding | endopeptidase activity | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | ubiquitin-dependent protein binding | peptidase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
metallopeptidase activity | protein homooligomerization | positive regulation of cellular component organization | proteolysis | negative regulation of cellular process | regulation of protein oligomerization | negative regulation of proteolysis | insulin catabolic process | cellular process | organic substance catabolic process | cellular homeostasis | proteolysis involved in cellular protein catabolic process | metalloendopeptidase activity | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | cellular component organization | cellular protein catabolic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular component assembly | drug catabolic process | nitrogen compound metabolic process | multicellular organism development | protein complex oligomerization | regulation of hormone levels | protein catabolic process | regulation of nitrogen compound metabolic process | amyloid-beta clearance | positive regulation of protein complex assembly | cellular amide metabolic process | protein homotetramerization | regulation of cellular protein metabolic process | protein tetramerization | regulation of cellular metabolic process | regulation of protein metabolic process | homeostatic process | peptide metabolic process | drug metabolic process | protein-containing complex assembly | protein metabolic process | hormone catabolic process | cellular macromolecule catabolic process | peptide catabolic process | anatomical structure development | metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of cellular protein metabolic process | insulin metabolic process | negative regulation of protein metabolic process | organonitrogen compound catabolic process | multicellular organism aging | bradykinin catabolic process | endopeptidase activity | ubiquitin recycling | determination of adult lifespan | cellular protein metabolic process | hormone metabolic process | protein heterooligomerization | developmental process | positive regulation of protein oligomerization | amyloid-beta metabolic process | cellular metabolic process | peptidase activity | aging | regulation of cellular component organization | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
peroxisomal matrix | intracellular membrane-bounded organelle | catalytic complex | peroxisome | cell | cytoplasm | proteasome complex | intracellular organelle | protein-containing complex | plasma membrane | mitochondrion | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cytosolic proteasome complex | cytosol | cell surface | intracellular | membrane
