QuickView for THRB;jsessionid=EFCF40E3316BB50686F5E83E4F597464;jsessionid=45E2100C7E96F995270571F9BCBD6C16 (gene)
- Gene Symbol:
- Thrb
Rattus norvegicus - Full name:
- thyroid hormone receptor beta
- Synonyms:
- C-erba-beta, ERBA2, Nr1a2, RATT3REC, T3rec, TRbeta, thyroid hormone receptor beta, TRbeta2Delta, c-erbA-2, nuclear receptor subfamily 1 group A member 2, thyroid hormone receptor beta 3, thyroid hormone receptor beta2delta, thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
- Genomic Location:
- Chr 15: 9279950-9369380
- Description:
-
nuclear hormone receptor for triiodothyronine (T3); mediates the biological activities of thyroid hormone
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | enzyme binding | nucleic acid binding | steroid hormone receptor activity | chromatin binding | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | thyroid hormone binding | identical protein binding | ion binding | organic cyclic compound binding | hormone binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | zinc ion binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | chromatin DNA binding | protein dimerization activity | nuclear receptor transcription coactivator activity | RNA polymerase II regulatory region sequence-specific DNA binding | transition metal ion binding | transcription coregulator activity | metal ion binding | heterocyclic compound binding | thyroid hormone receptor activity
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | retinal cone cell apoptotic process | regulation of neurogenesis | regulation of cell development | eye development | response to hormone | neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | respiratory tube development | type I pneumocyte differentiation | nervous system development | neurogenesis | generation of neurons | sensory perception of mechanical stimulus | hormone-mediated signaling pathway | neural retina development | positive regulation of cellular biosynthetic process | cellular process | positive regulation of cartilage development | nuclear receptor activity | neuron development | transcription factor activity, direct ligand regulated sequence-specific DNA binding | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | lung epithelium development | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | positive regulation of chondrocyte differentiation | tissue development | regulation of cell differentiation | regulation of cellular process | cellular response to lipid | regulation of metabolic process | regulation of eye photoreceptor cell development | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | negative regulation of photoreceptor cell differentiation | retinal cone cell differentiation | thyroid gland development | response to stimulus | respiratory system development | female mating behavior | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of blood circulation | programmed cell death | regulation of female receptivity | reproduction | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | embryo development | regulation of triglyceride metabolic process | regulation of steroid metabolic process | eye photoreceptor cell differentiation | retinal cell apoptotic process | regulation of nucleic acid-templated transcription | apoptotic process | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of cartilage development | multicellular organism development | retina morphogenesis in camera-type eye | regulation of ossification | regulation of neuron differentiation | regulation of gene expression | response to lipid | nervous system process | positive regulation of cellular metabolic process | retinal cone cell development | animal organ morphogenesis | regulation of nitrogen compound metabolic process | neuron apoptotic process | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | regulation of cholesterol metabolic process | biosynthetic process | aromatic compound biosynthetic process | positive regulation of ossification | female courtship behavior | regulation of heart contraction | endocrine system development | sensory organ development | cell communication | regulation of cellular metabolic process | eye morphogenesis | sensory perception of sound | positive regulation of cell proliferation | transcription coactivator activity | regulation of RNA metabolic process | eye photoreceptor cell development | negative regulation of eye photoreceptor cell development | lung epithelial cell differentiation | neuron differentiation | multicellular organism reproduction | DNA-binding transcription factor activity | negative regulation of female receptivity | courtship behavior | response to organic substance | gland development | regulation of photoreceptor cell differentiation | retina development in camera-type eye | regulation of animal organ morphogenesis | anatomical structure development | reproductive behavior | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nuclear receptor transcription coactivator activity | embryonic organ development | mating behavior | behavior | regulation of chondrocyte differentiation | nucleobase-containing compound metabolic process | organic substance metabolic process | mating | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of neuron differentiation | gene expression | cellular response to steroid hormone stimulus | transcription, DNA-templated | lung development | intracellular receptor signaling pathway | camera-type eye development | sensory perception | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | camera-type eye morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | lung cell differentiation | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | photoreceptor cell development | transcription coregulator activity | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of lipid metabolic process | positive regulation of metabolic process | cellular metabolic process | photoreceptor cell differentiation | cellular response to organic substance | response to steroid hormone | negative regulation of cell development | sexual reproduction | thyroid hormone receptor activity | camera-type eye photoreceptor cell differentiation | negative regulation of cell differentiation | signal transduction | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular
