QuickView for TIP33;jsessionid=E0FFC118DC2DA5A57AF0F011BAD6EEBA;jsessionid=E2733929081C1E32FE225637FAF02B0C (gene)

Gene Symbol:

TFIP11 Homo sapiens

Full name:

tuftelin interacting protein 11

Synonyms:

NTR1, STIP, STIP-1, Spp382, TIP39, bK445C9.6, tuftelin-interacting protein 11, septin and tuftelin-interacting protein 1, sip1/tuftelin interacting protein

Genomic Location:

Chr 22: 25217893-25238437

Description:

This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein cont...

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This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

22q12.1

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