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QuickView for TJ6M;jsessionid=9ED6E76CF369AB9B97D6E696D745D1CA;jsessionid=89A992A29A8D62950DE4D39522AA5EF9 (gene)


Gene Symbol:
Atp6v0a2 Mus musculus Mus musculus
Full name:
ATPase, H+ transporting, lysosomal V0 subunit A2
Synonyms:
8430408C20Rik, AI385560, ATP6a2, AW489264, Atp6n1d, Atp6n2, C76904, ISF, J6B7, SHIF, Stv1, TJ6M, TJ6s, Tj6, V-ATPase 116 kDa, V-ATPase a2, V-type proton ATPase 116 kDa subunit a isoform 2, ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 2 (38kD), ATPase, H+ transporting, lysosomal V0 subunit a, T-cell expressing clone j6, V-type proton ATPase 116 kDa subunit a, immune suppressor factor J6B7, vacuolar proton translocating ATPase 116 kDa subunit a
Genomic Location:
Chr 5: 125079657-125097396
Description:
This gene encodes a subunit of vacuolar ATPase, a multimeric enzyme that localizes to intracellular vesicles and to the plasma membrane of specialized cells. The encoded protein is a component of the V(0) domain, which functions in proton translocation across membranes. Function of this gene is important in fetal-specific immune suppression during ...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_011596
Protein Names
Q9JHJ2
Q8VHU0
Q3U2X3
A4FU82
P15920



GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | proton transmembrane transporter activity | enzyme binding | transmembrane transporter activity | hydrolase activity | ATPase activity | pyrophosphatase activity | catalytic activity | ATPase binding | nucleoside-triphosphatase activity | cation transmembrane transporter activity | ATPase activity, coupled | proton-exporting ATPase activity | cation-transporting ATPase activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | protein binding | proton-transporting ATPase activity, rotational mechanism | hydrolase activity, acting on acid anhydrides | ATPase coupled ion transmembrane transporter activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

ATP hydrolysis coupled cation transmembrane transport | cellular response to increased oxygen levels | vacuolar acidification | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | proton transmembrane transporter activity | cellular chemical homeostasis | cellular process | proton transmembrane transport | localization | cellular homeostasis | transmembrane transporter activity | pH reduction | response to stimulus | intracellular pH reduction | ATP hydrolysis coupled transmembrane transport | metal ion homeostasis | response to oxygen levels | ATP hydrolysis coupled ion transmembrane transport | ion transmembrane transport | cation transmembrane transporter activity | proton-exporting ATPase activity | cellular ion homeostasis | cation-transporting ATPase activity | monovalent inorganic cation transport | cellular response to oxygen levels | active transmembrane transporter activity | ion transmembrane transporter activity | ATP hydrolysis coupled proton transport | cation homeostasis | cellular cation homeostasis | regulation of intracellular pH | homeostatic process | iron ion homeostasis | cation transmembrane transport | regulation of pH | proton-transporting ATPase activity, rotational mechanism | chemical homeostasis | energy coupled proton transmembrane transport, against electrochemical gradient | ion homeostasis | inorganic cation transmembrane transport | cellular iron ion homeostasis | regulation of cellular pH | ATPase coupled ion transmembrane transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | cellular monovalent inorganic cation homeostasis | monovalent inorganic cation transmembrane transporter activity | cation transport | cellular metal ion homeostasis | ion transport | transition metal ion homeostasis

GO Cellular Component

secretory granule | proton-transporting V-type ATPase, V0 domain | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | proton-transporting V-type ATPase complex | cell | intrinsic component of membrane | cytoplasm | acrosomal vesicle | intracellular organelle | vacuolar proton-transporting V-type ATPase complex | vacuolar proton-transporting V-type ATPase, V0 domain | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | vacuole | vesicle | endosome | membrane-bounded organelle | organelle | cell periphery | proton-transporting two-sector ATPase complex | intracellular vesicle | intracellular | membrane | proton-transporting two-sector ATPase complex, proton-transporting domain | vacuolar membrane