QuickView for TOP2A;jsessionid=2E8415F1A4A7C1050B8411064AD58138;jsessionid=91AFECCCF5CEE35E6412FBB4F5DCA7D1 (gene)
- Gene Symbol:
- top2a
Danio rerio - Full name:
- topoisomerase (DNA) II alpha
- Synonyms:
- fc08c07, MGC92574, wu:fc08c07
- Genomic Location:
- Chr 12: 9006181-9023480
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
isomerase activity | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | DNA topoisomerase type II (ATP-hydrolyzing) activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA topoisomerase II activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | drug binding | heterocyclic compound binding | DNA topoisomerase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | negative regulation of cellular process | positive regulation of cellular biosynthetic process | cellular process | mitotic DNA integrity checkpoint | resolution of meiotic recombination intermediates | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regeneration | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | chromosome segregation | reproduction | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | DNA recombination | meiotic chromosome segregation | meiotic chromosome separation | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | sister chromatid segregation | regulation of gene expression | cell cycle | chromosome condensation | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | nuclear chromosome segregation | DNA topological change | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of mitotic cell cycle | DNA metabolic process | reciprocal meiotic recombination | anatomical structure development | mitotic cell cycle | nuclear division | metabolic process | regulation of RNA biosynthetic process | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | DNA packaging | meiosis I | negative regulation of cell cycle | meiotic cell cycle | regulation of transcription, DNA-templated | homologous recombination | developmental process | organelle organization | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | DNA conformation change | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | mitotic cell cycle checkpoint | cellular metabolic process | chromosome separation | cell cycle checkpoint | animal organ regeneration | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | DNA topoisomerase complex (ATP-hydrolyzing) | cell | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | intracellular
