QuickView for TOP2A;jsessionid=2E8415F1A4A7C1050B8411064AD58138;jsessionid=F329510071A889FD0A800481281A7A4F (gene)
- Gene Symbol:
- top-2
C. elegans - Full name:
- TOPoisomerase
- Synonyms:
- K12D12.1, top-2, Top-2
- Genomic Location:
- Chr II: 11875073-11880504
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cation binding | isomerase activity | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | DNA topoisomerase type II (ATP-hydrolyzing) activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA topoisomerase II activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | drug binding | metal ion binding | heterocyclic compound binding | DNA topoisomerase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
negative regulation of cellular process | cellular process | mitotic DNA integrity checkpoint | resolution of meiotic recombination intermediates | regulation of cell cycle | regulation of cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | chromosome segregation | reproduction | cellular nitrogen compound metabolic process | DNA recombination | meiotic chromosome segregation | meiotic chromosome separation | nitrogen compound metabolic process | reproductive process | sister chromatid segregation | cell cycle | cell division | nuclear chromosome segregation | DNA topological change | mitotic sister chromatid separation | regulation of mitotic cell cycle | DNA metabolic process | reciprocal meiotic recombination | mitotic cell cycle | nuclear division | metabolic process | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | mitotic nuclear division | meiosis I | negative regulation of cell cycle | meiotic cell cycle | homologous recombination | organelle organization | DNA conformation change | heterocycle metabolic process | chromosome organization | mitotic cell cycle checkpoint | cellular metabolic process | chromosome separation | cell cycle checkpoint | mitotic sister chromatid segregation | macromolecule metabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | spindle | intracellular organelle | nucleoplasm | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoskeleton | intracellular
