QuickView for TRG-5;jsessionid=C5FDAF26737F316882B414F12C39D730 (gene)

Gene Symbol:

Ldhb Rattus norvegicus

Full name:

lactate dehydrogenase B

Synonyms:

Ldh2, L-lactate dehydrogenase B chain, LDH heart subunit, LDH-B, LDH-H, Lactate dehydrogenease B

Genomic Location:

Chr 4: 180061567-180079473

Description:

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have also been found for this gene. Recent studies have shown that a C-terminally extended isoform is p...

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This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have also been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 9.

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Orthologs:

Homo sapiens ,  Mus musculus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP3_Q3 ,  T3R_Q6 ,  YGTCCTTGR_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  TGGAAA_NFAT_Q4_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-139

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