QuickView for TXAS;jsessionid=79F6E9F0A5825B30B22337D39610DB19;jsessionid=00901F4F3DD9EF24DA9133AE1C60872D (gene)
- Gene Symbol:
- Tbxas1
Rattus norvegicus - Full name:
- thromboxane A synthase 1
- Synonyms:
- thromboxane-A synthase, TXA synthase, TXS, ThromboxA ane synthase 1, cytochrome P450 5A1, thromboxane A synthase 1, platelet
- Genomic Location:
- Chr 4: 66502253-66677538
- Description:
-
catalyzes the conversion of prostaglandin H2 into thromboxane A2; mRNA expression increases in a model of hydronephrotic kidney; may play a role in response to injury
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | isomerase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | intramolecular oxidoreductase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | thromboxane-A synthase activity | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
regulation of blood vessel diameter | positive regulation of blood circulation | response to drug | cellular chemical homeostasis | response to antibiotic | cellular process | unsaturated fatty acid biosynthetic process | cellular homeostasis | anion homeostasis | positive regulation of vasoconstriction | icosanoid biosynthetic process | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | regulation of blood vessel size | regulation of blood circulation | cellular monovalent inorganic anion homeostasis | response to alcohol | blood circulation | cellular biosynthetic process | response to ethanol | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | response to fatty acid | lipid metabolic process | response to lipid | cellular ion homeostasis | small molecule metabolic process | fatty acid biosynthetic process | biosynthetic process | lipid biosynthetic process | response to toxic substance | homeostatic process | regulation of tube size | carboxylic acid metabolic process | cellular chloride ion homeostasis | response to organic substance | chloride ion homeostasis | regulation of vasoconstriction | metabolic process | oxidation-reduction process | regulation of tube diameter | chemical homeostasis | prostaglandin metabolic process | organic substance metabolic process | ion homeostasis | fatty acid metabolic process | icosanoid metabolic process | organic acid metabolic process | prostaglandin biosynthetic process | cellular metabolic process | oxidoreductase activity | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
