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QuickView for Tex8;jsessionid=D8BE423427017D78E977D639CEED1B5B;jsessionid=EE8794168F36360F5FBFCA3287DD542F (gene)


Gene Symbol:
CAPZA3 Homo sapiens Homo sapiens
Full name:
capping actin protein of muscle Z-line alpha subunit 3
Synonyms:
CAPPA3, Gsg3, HEL-S-86, F-actin-capping protein subunit alpha-3, CP-alpha-3, CapZ alpha-3, F-actin capping protein alpha-3 subunit, capping protein (actin filament) muscle Z-line, alpha 3, epididymis secretory protein Li 86, germ cell-specific protein 3, testis tissue sperm-binding protein Li 73n
Genomic Location:
Chr 12: 18782312-18783389
Description:
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. Thi...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 12
12p12.3


Transcripts Names
NM_033328
Protein Names
A0A140VKF6
Q96KX2
Q969J0



GO Molecular Function

actin binding | actin filament binding | protein-containing complex binding | cytoskeletal protein binding | protein binding

GO Biological Process

regulation of supramolecular fiber organization | actin filament-based process | antigen processing and presentation | developmental process involved in reproduction | negative regulation of protein complex disassembly | actin cytoskeleton organization | establishment of localization | negative regulation of cellular process | cell differentiation | male gamete generation | regulation of organelle organization | regulation of actin polymerization or depolymerization | intracellular transport | cellular process | localization | multicellular organismal reproductive process | establishment of localization in cell | gamete generation | regulation of cellular process | regulation of protein complex assembly | cellular component organization | regulation of actin filament length | germ cell development | reproduction | cellular localization | antigen processing and presentation of exogenous peptide antigen via MHC class II | regulation of cellular component size | spermatid differentiation | actin filament capping | reproductive process | antigen processing and presentation of peptide antigen via MHC class II | regulation of actin cytoskeleton organization | regulation of actin filament organization | regulation of protein complex disassembly | negative regulation of actin filament polymerization | vesicle-mediated transport | regulation of actin filament polymerization | regulation of actin filament depolymerization | Golgi vesicle transport | regulation of protein depolymerization | multicellular organism reproduction | antigen processing and presentation of exogenous antigen | negative regulation of protein polymerization | anatomical structure development | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | negative regulation of cytoskeleton organization | negative regulation of protein complex assembly | spermatid development | barbed-end actin filament capping | cytoskeleton organization | negative regulation of actin filament depolymerization | ER to Golgi vesicle-mediated transport | cell development | developmental process | organelle organization | spermatogenesis | antigen processing and presentation of peptide antigen | negative regulation of supramolecular fiber organization | regulation of actin filament-based process | immune system process | sexual reproduction | regulation of cellular component organization | regulation of cytoskeleton organization | multicellular organismal process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | F-actin capping protein complex | actin cortical patch | cytoplasmic vesicle | cell | cytoplasm | cortical cytoskeleton | acrosomal vesicle | intracellular organelle | actin cytoskeleton | protein-containing complex | secretory vesicle | endomembrane system | vesicle | endocytic patch | cytoplasmic region | cortical actin cytoskeleton | cell cortex | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular vesicle | cytoskeleton | intracellular | membrane