QuickView for Tnfaip3;jsessionid=7A81D5338B92F27881B880B5D8D7C678;jsessionid=DC5374B5845E3B30FCC9C8A15EBD8FCE (gene)
- Gene Symbol:
- Tnfaip3
Mus musculus - Full name:
- tumor necrosis factor, alpha-induced protein 3
- Synonyms:
- A20, Tnfip3, tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, putative DNA-binding protein A20, tumor necrosis factor induced protein 3, zinc finger protein A20
- Genomic Location:
- Chr 10: 18720722-18735173
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
protein self-association | kinase binding | K63-linked polyubiquitin modification-dependent protein binding | cation binding | enzyme binding | nucleic acid binding | thiol-dependent ubiquitinyl hydrolase activity | hydrolase activity | ubiquitin binding | cysteine-type peptidase activity | catalytic activity | polyubiquitin modification-dependent protein binding | ubiquitin-like protein transferase activity | modification-dependent protein binding | DNA binding | identical protein binding | ubiquitin-like protein binding | thiol-dependent ubiquitin-specific protease activity | ion binding | organic cyclic compound binding | Lys63-specific deubiquitinase activity | protein binding | ubiquitinyl hydrolase activity | zinc ion binding | ubiquitin-protein transferase activity | transferase activity | transition metal ion binding | protease binding | metal ion binding | heterocyclic compound binding | peptidase activity
GO Biological Process
protein modification by small protein removal | leukocyte homeostasis | negative regulation of leukocyte activation | negative regulation of phosphorylation | regulation of interleukin-1 beta production | negative regulation of immune system process | regulation of B cell activation | cell motility | response to lipopolysaccharide | proteolysis | protein localization to vacuole | regulation of programmed cell death | establishment of localization | regulation of autophagy | regulation of immune system process | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of developmental process | cell differentiation | positive regulation of epithelial cell proliferation | regulation of toll-like receptor 3 signaling pathway | defense response | tolerance induction to lipopolysaccharide | positive regulation of protein catabolic process | response to drug | negative regulation of protein phosphorylation | negative regulation of chronic inflammatory response | B cell differentiation | response to antibiotic | negative regulation of granuloma formation | cellular process | organic substance catabolic process | negative regulation of inflammatory response | lymphocyte differentiation | localization | proteolysis involved in cellular protein catabolic process | negative regulation of signaling | regulation of embryonic development | tolerance induction | immune system development | negative regulation of innate immune response | macromolecule localization | regulation of CD40 signaling pathway | negative regulation of apoptotic process | regulation of hepatocyte proliferation | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | protein K11-linked deubiquitination | response to inorganic substance | negative regulation of cellular metabolic process | negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | negative regulation of apoptotic signaling pathway | response to hydrogen peroxide | regulation of immune response | regulation of cellular process | leukocyte activation | negative regulation of interleukin-1 production | regulation of apoptotic process | negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway | cellular response to lipid | regulation of metabolic process | catabolic process | cellular response to molecule of bacterial origin | negative regulation of tumor necrosis factor production | negative regulation of toll-like receptor 5 signaling pathway | positive regulation of cellular protein metabolic process | cellular component organization | protein deubiquitination | negative regulation of toll-like receptor signaling pathway | thiol-dependent ubiquitinyl hydrolase activity | positive regulation of cellular protein catabolic process | response to stimulus | negative regulation of epithelial cell apoptotic process | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | negative regulation of cell adhesion | response to stress | regulation of heterotypic cell-cell adhesion | negative regulation of tumor necrosis factor superfamily cytokine production | negative regulation of lymphocyte activation | leukocyte activation involved in immune response | negative regulation of protein kinase activity | negative regulation of CD40 signaling pathway | mature B cell differentiation | regulation of cell proliferation | regulation of protein ubiquitination | response to peptide | response to muramyl dipeptide | programmed cell death | cellular protein catabolic process | cellular localization | response to molecule of bacterial origin | regulation of granuloma formation | cellular response to toxic substance | protein K33-linked deubiquitination | protein K48-linked deubiquitination | negative regulation of metabolic process | hemopoiesis | protein modification process | regulation of cell adhesion | macromolecule modification | cysteine-type peptidase activity | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | leukocyte differentiation | locomotion | response to nitrogen compound | apoptotic process | response to external biotic stimulus | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | cellular response to antibiotic | negative regulation of interleukin-6 production | multicellular organism development | negative regulation of catalytic activity | cell migration | regulation of toll-like receptor signaling pathway | marginal zone B cell differentiation | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | cellular response to oxidative stress | regulation of phosphorylation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | response to lipid | protein catabolic process | negative regulation of cyclin-dependent protein serine/threonine kinase activity | negative regulation of cytokine production | positive regulation of cellular metabolic process | regulation of lymphocyte activation | negative regulation of smooth muscle cell proliferation | regulation of germinal center formation | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | negative regulation of DNA-binding transcription factor activity | negative regulation of protein serine/threonine kinase activity | regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway | regulation of endothelial cell apoptotic process | response to oxidative stress | negative regulation of toll-like receptor 3 signaling pathway | B cell homeostasis | protein localization to organelle | negative regulation of heterotypic cell-cell adhesion | mature B cell differentiation involved in immune response | negative regulation of extrinsic apoptotic signaling pathway | homeostasis of number of cells | B cell activation | regulation of cellular protein metabolic process | negative regulation of immune response | thiol-dependent ubiquitin-specific protease activity | response to toxic substance | regulation of apoptotic signaling pathway | regulation of epithelial cell apoptotic process | regulation of tumor necrosis factor production | negative regulation of autophagy | cellular response to drug | response to bacterium | regulation of interleukin-1 production | negative regulation of cell-cell adhesion | regulation of cellular metabolic process | regulation of protein kinase activity | lymphocyte homeostasis | negative regulation of cell activation | inflammatory response | cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | negative regulation of interleukin-2 production | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | negative regulation of protein ubiquitination | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | regulation of nucleotide-binding oligomerization domain containing signaling pathway | Lys63-specific deubiquitinase activity | negative regulation of B cell activation | lymphocyte activation | protein polyubiquitination | negative regulation of cyclin-dependent protein kinase activity | protein metabolic process | protein K63-linked deubiquitination | protein deubiquitination involved in ubiquitin-dependent protein catabolic process | response to organic substance | regulation of innate immune response | protein ubiquitination | regulation of kinase activity | response to wounding | regulation of lipopolysaccharide-mediated signaling pathway | regulation of animal organ morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cellular macromolecule catabolic process | establishment of protein localization to organelle | anatomical structure development | regulation of chronic inflammatory response | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of adaptive immune response | regulation of RNA biosynthetic process | negative regulation of programmed cell death | cellular protein localization | regulation of cell-cell adhesion involved in gastrulation | cellular response to hydrogen peroxide | immune response | cellular response to reactive oxygen species | organic substance metabolic process | cell death | animal organ development | response to reactive oxygen species | negative regulation of cellular protein metabolic process | regulation of cell activation | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | establishment of protein localization to vacuole | cytoskeleton organization | establishment of protein localization | cell activation | ubiquitin-dependent protein catabolic process | negative regulation of cell cycle | negative regulation of protein metabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | regulation of immunoglobulin production | regulation of transcription, DNA-templated | protein localization | regulation of epithelial cell proliferation | B cell activation involved in immune response | cellular protein metabolic process | regulation of cytokine production | cellular macromolecule localization | response to biotic stimulus | regulation of developmental process | developmental process | organelle organization | cellular protein modification process | negative regulation of interleukin-1 beta production | protein K29-linked deubiquitination | regulation of gastrulation | negative regulation of cell proliferation | regulation of cell-cell adhesion | response to organonitrogen compound | positive regulation of hepatocyte proliferation | protein K48-linked ubiquitination | positive regulation of metabolic process | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of lipopolysaccharide-mediated signaling pathway | peptidase activity | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | modification-dependent protein catabolic process | negative regulation of cell death | regulation of interleukin-6 production | regulation of inflammatory response | B-1 B cell homeostasis | regulation of I-kappaB kinase/NF-kappaB signaling | response to other organism | positive regulation of signaling | regulation of signaling | negative regulation of endothelial cell apoptotic process | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | vacuole | lytic vacuole | membrane-bounded organelle | nucleus | organelle | lysosome | intracellular
