QuickView for UBXN11;jsessionid=24634F57EA44AE5724CCADDF3B0F3778;jsessionid=F8FF8D446998CEF1A5A3AF54666F5BFD;jsessionid=816A27F09CD9D8DB0C1DFDDC0E9BDEDA;jsessionid=445FCD8FD9BB99C158029F23B6D9CF3A;jsessionid=27CDF1A16828DB72F8D38D42AB15C931;jsessionid=9B527B1C4AC73DA7CC6731FADA38AA64 (gene)

Gene Symbol:: UBXN11 Homo sapiens
Full name:: UBX domain protein 11
Synonyms:: COA-1, PP2243, SOC, SOCI, UBXD5, UBX domain-containing protein 11, UBX domain-containing protein 5, colorectal tumor-associated antigen COA-1, colorectal tumor-associated antigen-1, socius
Genomic Location:: Chr 1: 26481360-26517343
Description:: This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is propos...
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This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.
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