QuickView for UGT8;jsessionid=A32FB05027A1B9EF11EBBB2D43AD1E3E;jsessionid=A7386B0FF078083C8C31D5C3C256969B;jsessionid=739740B32E6826405896D5E08437C420;jsessionid=209A53B5744A1E82BF789F97BB3040F9 (gene)
- Gene Symbol:
- Ugt8
Rattus norvegicus - Full name:
- UDP glycosyltransferase 8
- Synonyms:
- Ugt8a, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, UDP galactosyltransferase 8, UDP galactosyltransferase 8A, UDP-galactose-ceramide galactosyltransferase 8, UDP-glucuronosyltransferase 8, ceramide UDP-galactosyltransferase, cerebroside synthase
- Genomic Location:
- Chr 2: 222977966-223048277
- Description:
-
catalyzes the synthesis of galactocerebroside (Galc); important for the development and maintainance of the myelin membranes of the nervous system
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
UDP-galactosyltransferase activity | N-acylsphingosine galactosyltransferase activity | UDP-glycosyltransferase activity | catalytic activity | transferase activity, transferring glycosyl groups | transferase activity, transferring hexosyl groups | transferase activity | galactosyltransferase activity | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity
GO Biological Process
cell morphogenesis | neuron projection morphogenesis | glycosphingolipid metabolic process | glycolipid biosynthetic process | cell differentiation | protein localization to axon | nervous system development | cell part morphogenesis | neurogenesis | generation of neurons | cellular process | localization | axon ensheathment | cell projection morphogenesis | neuron development | macromolecule localization | sphingolipid metabolic process | paranodal junction assembly | galactosylceramide biosynthetic process | cell junction assembly | cellular component organization | cellular lipid metabolic process | glycosphingolipid biosynthetic process | cellular nitrogen compound biosynthetic process | ceramide metabolic process | ensheathment of neurons | sphingolipid biosynthetic process | cellular localization | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cellular component assembly | cellular biosynthetic process | system development | nitrogen compound metabolic process | myelination | multicellular organism development | lipid metabolic process | galactosylceramide metabolic process | cellular amide metabolic process | glycolipid metabolic process | biosynthetic process | lipid biosynthetic process | glycosylceramide metabolic process | neuron differentiation | anatomical structure development | cell projection organization | metabolic process | membrane lipid metabolic process | cell-cell junction assembly | cellular protein localization | neuron projection development | organic substance metabolic process | amide biosynthetic process | cytoskeleton organization | anatomical structure formation involved in morphogenesis | cell development | protein localization | anatomical structure morphogenesis | cellular macromolecule localization | developmental process | organelle organization | myelin assembly | carbohydrate derivative metabolic process | cellular metabolic process | ceramide biosynthetic process | protein localization to paranode region of axon | multicellular organismal process | cell-cell junction organization
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | intracellular organelle | membrane-bounded organelle | organelle | intracellular | membrane
