QuickView for VEGFR;jsessionid=6ED3CEFFA7F3F589B21D080ED033AF07;jsessionid=EB273F344051EDB1E8E09DDD8B495452 (gene)
- Gene Symbol:
- Kdr
Mus musculus - Full name:
- kinase insert domain protein receptor
- Synonyms:
- 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, orv, sVEGFR-2, vascular endothelial growth factor receptor 2, VEGF receptor-2, fetal liver kinase 1, kinase NYK, protein-tyrosine kinase receptor flk-1, soluble vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor-3
- Genomic Location:
- Chr 5: 76329290-76374453
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Gallus gallus , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
transmembrane receptor protein tyrosine kinase activity | vascular endothelial growth factor binding | transmembrane signaling receptor activity | protein-containing complex binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | growth factor binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | vascular endothelial growth factor-activated receptor activity | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | integrin binding | organic cyclic compound binding | cell adhesion molecule binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | regulation of blood vessel diameter | cell morphogenesis | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | positive regulation of adherens junction organization | developmental process involved in reproduction | intracellular signal transduction | ovarian follicle development | regulation of cell development | regulation of localization | morphogenesis of an epithelium | gonad development | regulation of programmed cell death | female gonad development | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | regulation of mitochondrial fission | eye development | regulation of autophagy | blood vessel endothelial cell migration | regulation of immune system process | regulation of cell shape | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of endothelial cell chemotaxis | endothelial cell differentiation | respiratory tube development | nervous system development | response to drug | organ growth | regulation of hematopoietic progenitor cell differentiation | regulation of sprouting angiogenesis | epithelial cell migration | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | post-embryonic animal organ morphogenesis | regulation of organelle organization | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | generation of neurons | tissue homeostasis | positive regulation of vascular endothelial growth factor receptor signaling pathway | blood vessel morphogenesis | regulation of neuron death | cellular process | regulation of cell motility | localization | cellular homeostasis | cell projection morphogenesis | epithelial tube morphogenesis | cell maturation | regulation of calcium-mediated signaling | regulation of mitochondrial membrane potential | negative regulation of signaling | developmental growth | neuron development | regulation of neuronal synaptic plasticity | reproductive system development | response to hydrogen sulfide | regulation of vascular endothelial growth factor receptor signaling pathway | epithelium migration | immune system development | regulation of chemotaxis | negative regulation of apoptotic process | response to hypoxia | response to growth factor | positive regulation of nitrogen compound metabolic process | response to inorganic substance | tissue development | regulation of cell differentiation | anatomical structure homeostasis | regulation of angiogenesis | peptidyl-tyrosine autophosphorylation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | epithelium development | regulation of mitochondrial depolarization | cellular component organization | MAPK cascade | calcium ion homeostasis | positive regulation of epithelial cell migration | development of primary sexual characteristics | sprouting angiogenesis | blood vessel endothelial cell differentiation | regulation of vasculature development | response to stimulus | negative regulation of epithelial cell apoptotic process | vasculature development | cellular response to vascular endothelial growth factor stimulus | respiratory system development | positive regulation of mitochondrial depolarization | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | regulation of blood vessel size | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | endothelial cell migration | post-embryonic camera-type eye development | regulation of cell proliferation | multicellular organismal homeostasis | tube morphogenesis | regulation of epithelial cell differentiation | development of primary female sexual characteristics | reproduction | cardiovascular system development | positive regulation of sprouting angiogenesis | cellular response to toxic substance | regulation of macroautophagy | positive regulation of blood vessel endothelial cell migration | blood circulation | negative regulation of metabolic process | positive regulation of BMP signaling pathway | hemopoiesis | protein modification process | modulation of chemical synaptic transmission | regulation of cell adhesion | embryo development | macromolecule modification | regulation of TOR signaling | positive regulation of cell-matrix adhesion | metal ion homeostasis | positive regulation of mitochondrion organization | blood vessel development | regulation of nucleic acid-templated transcription | regulation of membrane potential | locomotion | negative regulation of neuron apoptotic process | regulation of long-term neuronal synaptic plasticity | lung alveolus development | protein kinase B signaling | chemical homeostasis within a tissue | positive regulation of cell junction assembly | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | endothelium development | post-embryonic animal organ development | regulation of adherens junction organization | multicellular organism development | cell migration | regulation of MAPK cascade | regulation of BMP signaling pathway | phosphorus metabolic process | embryonic hemopoiesis | lymph vessel development | regulation of phosphorylation | post-embryonic camera-type eye morphogenesis | regulation of gene expression | vascular endothelial growth factor-activated receptor activity | positive regulation of chemotaxis | regulation of membrane depolarization | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | animal organ morphogenesis | positive regulation of cytosolic calcium ion concentration | vascular endothelial growth factor signaling pathway | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | enzyme linked receptor protein signaling pathway | bone growth | post-embryonic animal morphogenesis | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | regulation of endothelial cell apoptotic process | regulation of cell migration involved in sprouting angiogenesis | positive regulation of cell differentiation | regulation of endothelial cell migration | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway | second-messenger-mediated signaling | positive regulation of calcium-mediated signaling | positive regulation of cell migration | positive regulation of long-term neuronal synaptic plasticity | regulation of cellular protein metabolic process | positive regulation of cell migration by vascular endothelial growth factor signaling pathway | angiogenesis | surfactant homeostasis | phosphorylation | response to toxic substance | regulation of epithelial cell apoptotic process | protein phosphorylation | post-embryonic development | cation homeostasis | phosphate-containing compound metabolic process | sensory organ development | cellular response to drug | regulation of mitochondrion organization | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | eye morphogenesis | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | heart development | cellular calcium ion homeostasis | positive regulation of TOR signaling | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | post-embryonic eye morphogenesis | regulation of RNA metabolic process | regulation of tube size | regulation of cellular response to growth factor stimulus | protein tyrosine kinase activity | calcium-mediated signaling | neuron differentiation | development of primary male sexual characteristics | protein metabolic process | positive regulation of focal adhesion assembly | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | regulation of hemopoiesis | branching morphogenesis of an epithelial tube | endocardium development | male sex differentiation | regulation of intracellular signal transduction | regulation of bone development | regulation of focal adhesion assembly | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | cell projection organization | metabolic process | positive regulation of cell development | cell fate commitment | regulation of RNA biosynthetic process | developmental maturation | negative regulation of programmed cell death | embryonic organ development | male gonad development | regulation of tube diameter | chemical homeostasis | protein kinase activity | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of gene expression | animal organ development | regulation of endothelial cell proliferation | positive regulation of cell-substrate adhesion | positive regulation of ERK1 and ERK2 cascade | ion homeostasis | regulation of phosphate metabolic process | regulation of vasculogenesis | positive regulation of autophagy | positive regulation of macroautophagy | positive regulation of endothelial cell migration | positive regulation of MAPK cascade | lung development | morphogenesis of a branching epithelium | camera-type eye development | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | positive regulation of vasculogenesis | regulation of cell communication | regulation of blood vessel endothelial cell migration | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | cell development | positive regulation of cell migration involved in sprouting angiogenesis | positive regulation of mitochondrial fission | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | camera-type eye morphogenesis | reproductive structure development | regulation of nervous system development | regulation of developmental process | kinase activity | regulation of mesenchymal cell proliferation | developmental process | cellular protein modification process | vascular endothelial growth factor receptor signaling pathway | calcium-mediated signaling using intracellular calcium source | tube development | regulation of cell junction assembly | cell migration involved in sprouting angiogenesis | positive regulation of mesenchymal cell proliferation | regulation of endothelial cell differentiation | cellular metal ion homeostasis | epithelial cell differentiation | ERK1 and ERK2 cascade | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | regulation of synaptic plasticity | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | female sex differentiation | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cell motility | negative regulation of cell death | positive regulation of blood vessel diameter | circulatory system development | cellular response to hydrogen sulfide | endochondral bone growth | divalent inorganic cation homeostasis | positive regulation of angiogenesis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | negative regulation of endothelial cell apoptotic process | positive regulation of nitric-oxide synthase biosynthetic process | regulation of cell-matrix adhesion | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | positive regulation of positive chemotaxis | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | membrane microdomain | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | membrane raft | vesicle | integral component of plasma membrane | endosome | extracellular region | membrane-bounded organelle | nucleus | organelle | cell periphery | early endosome | intracellular vesicle | cell surface | intracellular | cell junction | sorting endosome | membrane | intrinsic component of plasma membrane
