QuickView for acl;jsessionid=5413DCB73AF0264F1B3E64A044750076;jsessionid=77CA5A49A80506DD49121412EB992CAA (gene)
- Gene Symbol:
- Acly
Rattus norvegicus - Full name:
- ATP citrate lyase
- Synonyms:
- ACL, Clatp, ATP-citrate synthase, ATP-citrate (pro-S-)-lyase, citrate cleavage enzyme
- Genomic Location:
- Chr 10: 89420941-89471349
- Description:
-
catalyzes the synthesis of cytosolic acetyl-CoA; plays a role in lipid and cholesterol metabolism
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cofactor binding | cation binding | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | lyase activity | catalytic activity | ATP binding | transferase activity, transferring acyl groups | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | transferase activity | ATP citrate synthase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
purine ribonucleotide metabolic process | sulfur compound metabolic process | acetyl-CoA biosynthetic process | cellular process | dicarboxylic acid metabolic process | nucleotide metabolic process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | purine nucleotide metabolic process | monocarboxylic acid metabolic process | cellular nitrogen compound biosynthetic process | acetyl-CoA metabolic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular biosynthetic process | nucleotide biosynthetic process | nitrogen compound metabolic process | coenzyme biosynthetic process | antibiotic metabolic process | phosphorus metabolic process | acyl-CoA metabolic process | lipid metabolic process | organophosphate metabolic process | cofactor biosynthetic process | small molecule metabolic process | cellular amide metabolic process | nucleobase-containing small molecule metabolic process | fatty acid biosynthetic process | biosynthetic process | aromatic compound biosynthetic process | purine ribonucleotide biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | oxaloacetate metabolic process | drug metabolic process | carboxylic acid metabolic process | tricarboxylic acid metabolic process | metabolic process | citrate metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | amide biosynthetic process | fatty acid metabolic process | ribose phosphate biosynthetic process | organic acid metabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | plasma membrane | membrane-bounded organelle | nucleus | organelle | citrate lyase complex | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
