QuickView for cbl2;jsessionid=0AAF7C8D17F913F3E1307BBA5863BB1B;jsessionid=C2A8712F3B2882CF6BCCF78BA285F97D (gene)
- Gene Symbol:
- Cbl
Mus musculus - Full name:
- Casitas B-lineage lymphoma
- Synonyms:
- 4732447J05Rik, Cbl-2, c-Cbl, cbl, E3 ubiquitin-protein ligase CBL, RING-type E3 ubiquitin transferase CBL, casitas B-lineage lymphoma proto-oncogene, proto-oncogene c-CBL, signal transduction protein CBL
- Genomic Location:
- Chr 9: 43957345-44042129
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-1 , Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-133 , Predicted Gene Targets for miR-150 , Predicted Gene Targets for miR-192 , Predicted Gene Targets for miR-199 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-214 , Predicted Gene Targets for miR-218
GO Molecular Function
protein phosphorylated amino acid binding | phosphatidylinositol 3-kinase binding | ephrin receptor binding | kinase binding | cation binding | protein kinase binding | receptor tyrosine kinase binding | enzyme binding | phosphotyrosine residue binding | SH3 domain binding | signaling receptor binding | catalytic activity | protein domain specific binding | ubiquitin-like protein transferase activity | phosphatidylinositol 3-kinase regulatory subunit binding | ubiquitin protein ligase activity | ion binding | protein tyrosine kinase binding | phosphoprotein binding | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | epidermal growth factor receptor binding | calcium ion binding | growth factor receptor binding | metal ion binding
GO Biological Process
negative regulation of signaling receptor activity | negative regulation of phosphorylation | positive regulation of cellular component organization | proteolysis | regulation of localization | regulation of programmed cell death | negative regulation of neuron death | negative regulation of cellular process | negative regulation of kinase activity | negative regulation of protein phosphorylation | response to antibiotic | regulation of neuron death | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | negative regulation of signaling | negative regulation of apoptotic process | response to growth factor | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | negative regulation of epidermal growth factor receptor signaling pathway | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of phosphatidylinositol 3-kinase signaling | negative regulation of protein kinase activity | cellular protein catabolic process | negative regulation of metabolic process | protein modification process | macromolecule modification | regulation of protein tyrosine kinase activity | nitrogen compound metabolic process | regulation of signal transduction | protein monoubiquitination | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | regulation of phosphorylation | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | protein catabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | positive regulation of intracellular signal transduction | ubiquitin protein ligase activity | regulation of cellular protein metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | positive regulation of transport | protein polyubiquitination | cellular response to epidermal growth factor stimulus | regulation of signaling receptor activity | regulation of epidermal growth factor-activated receptor activity | protein metabolic process | response to organic substance | protein ubiquitination | regulation of kinase activity | regulation of intracellular signal transduction | cellular macromolecule catabolic process | cell surface receptor signaling pathway | metabolic process | ubiquitin-protein transferase activity | negative regulation of programmed cell death | regulation of vesicle-mediated transport | negative regulation of ERBB signaling pathway | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | negative regulation of cellular protein metabolic process | protein modification by small protein conjugation or removal | regulation of phosphate metabolic process | response to epidermal growth factor | ubiquitin-dependent protein catabolic process | negative regulation of protein metabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of ERBB signaling pathway | regulation of endocytosis | negative regulation of peptidyl-tyrosine phosphorylation | cellular protein metabolic process | negative regulation of epidermal growth factor-activated receptor activity | cellular protein modification process | regulation of transport | cellular metabolic process | cellular response to organic substance | regulation of cell death | modification-dependent protein catabolic process | negative regulation of protein tyrosine kinase activity | negative regulation of cell death | positive regulation of endocytosis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
neuron projection | adherens junction | focal adhesion | cell | plasma membrane protein complex | distal axon | cytoplasm | cell-substrate junction | membrane microdomain | protein-containing complex | cell projection | plasma membrane | membrane raft | perinuclear region of cytoplasm | site of polarized growth | flotillin complex | cell periphery | axon | cell-substrate adherens junction | growth cone | plasma membrane raft | cytosol | intracellular | cell junction | caveola | membrane
