QuickView for clusterin;jsessionid=BD210B3186B595F0690C766F3FEA9295;jsessionid=6998EE08A530966501E87460623E3489 (gene)
- Gene Symbol:
- CLU
Gallus gallus - Full name:
- clusterin
- Synonyms:
- N/A
- Genomic Location:
- Chr 3: 107997681-108001887
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATA1_01 , CEBP_Q2 , STAT_01 , LMO2COM_02 , STAT5B_01 , STAT_Q6 , GATA_Q6 , SYATTGTG_UNKNOWN , TCCATTKW_UNKNOWN , TTANWNANTGGM_UNKNOWN
GO Molecular Function
peptide binding | low-density lipoprotein particle receptor binding | amyloid-beta binding | enzyme binding | protein-containing complex binding | lipoprotein particle receptor binding | signaling receptor binding | ubiquitin-like protein ligase binding | cytoskeletal protein binding | tau protein binding | amide binding | protein binding | misfolded protein binding | ubiquitin protein ligase binding
GO Biological Process
negative regulation of amyloid-beta formation | regulation of supramolecular fiber organization | cell morphogenesis | glial cell proliferation | positive regulation of amyloid precursor protein catabolic process | response to virus | positive regulation of cellular component organization | protein stabilization | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | establishment of localization | negative regulation of protein homooligomerization | regulation of nitric oxide biosynthetic process | negative regulation of cellular process | cell differentiation | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | response to misfolded protein | nervous system development | positive regulation of protein catabolic process | negative regulation of cellular response to thapsigargin | positive regulation of tau-protein kinase activity | neurogenesis | positive regulation of phosphate metabolic process | regulation of protein oligomerization | membrane organization | microglial cell proliferation | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | localization | axon ensheathment | chaperone-mediated protein folding | protein transport | negative regulation of signaling | positive regulation of reactive oxygen species metabolic process | positive regulation of neurofibrillary tangle assembly | positive regulation of protein kinase activity | macromolecule localization | negative regulation of response to endoplasmic reticulum stress | negative regulation of apoptotic process | endomembrane system organization | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | myelin maintenance | central nervous system myelination | negative regulation of cellular metabolic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | gliogenesis | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | response to topologically incorrect protein | cellular component organization | positive regulation of tumor necrosis factor production | positive regulation of cellular protein catabolic process | response to stimulus | oligodendrocyte development | positive regulation of nitric oxide metabolic process | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | regulation of neuronal signal transduction | negative regulation of cellular response to tunicamycin | response to stress | regulation of response to endoplasmic reticulum stress | ensheathment of neurons | axon ensheathment in central nervous system | positive regulation of proteolysis involved in cellular protein catabolic process | positive regulation of proteolysis | negative regulation of protein oligomerization | negative regulation of metabolic process | cellular component assembly | negative regulation of amyloid precursor protein catabolic process | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | regulation of neurotransmitter levels | positive regulation of reactive oxygen species biosynthetic process | response to external biotic stimulus | system development | regulation of signal transduction | regulation of protein stability | myelination | multicellular organism development | negative regulation of amyloid fibril formation | regulation of tau-protein kinase activity | regulation of catalytic activity | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | plasma membrane organization | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | regulation of gene expression | organic substance transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | peptide transport | positive regulation of protein complex assembly | central nervous system myelin maintenance | cell proliferation | leukocyte proliferation | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | glial cell differentiation | cellular protein-containing complex assembly | positive regulation of neuron death | regulation of apoptotic signaling pathway | microglial cell activation | regulation of tumor necrosis factor production | regulation of amyloid precursor protein catabolic process | protein import | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | positive regulation of molecular function | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein-containing complex assembly | regulation of protein homooligomerization | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | chaperone-mediated protein complex assembly | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | regulation of amyloid fibril formation | regulation of proteasomal protein catabolic process | regulation of amyloid-beta clearance | oligodendrocyte differentiation | amide transport | regulation of vesicle-mediated transport | positive regulation of cell death | regulation of response to DNA damage stimulus | macrophage activation | negative regulation of protein complex assembly | positive regulation of cellular component biogenesis | negative regulation of intrinsic apoptotic signaling pathway | protein folding | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | positive regulation of NF-kappaB transcription factor activity | positive regulation of kinase activity | regulation of phosphate metabolic process | establishment of protein localization | positive regulation of cytokine production | cell activation | regulation of reactive oxygen species biosynthetic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | regulation of transcription, DNA-templated | glial cell development | regulation of amyloid-beta formation | cell development | positive regulation of protein homooligomerization | regulation of endocytosis | protein localization | positive regulation of phosphorylation | regulation of cytokine production | anatomical structure morphogenesis | response to biotic stimulus | developmental process | regulation of inclusion body assembly | positive regulation of inclusion body assembly | regulation of transport | regulation of reactive oxygen species metabolic process | positive regulation of protein oligomerization | negative regulation of supramolecular fiber organization | positive regulation of nitric oxide biosynthetic process | central nervous system development | positive regulation of metabolic process | immune system process | positive regulation of amyloid-beta formation | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | positive regulation of endocytosis | regulation of cellular component organization | response to other organism | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell | spherical high-density lipoprotein particle | cytoplasm | intracellular organelle | lipoprotein particle | dendritic tree | inclusion body | protein-containing complex | cell projection | protein-lipid complex | perinuclear region of cytoplasm | mitochondrion | extracellular region | membrane-bounded organelle | nucleus | organelle | high-density lipoprotein particle | extracellular space | apical dendrite | cell periphery | plasma lipoprotein particle | cell surface | cytoskeleton | intracellular | neurofibrillary tangle | membrane
