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QuickView for cyp4a;jsessionid=CBC882B9D08D8AAB39B33D833F236E50;jsessionid=1A311D816C8730F6051CE8826CA41F29 (gene)


Gene Symbol:
CYP4A11 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 4 subfamily A member 11
Synonyms:
CP4Y, CYP4A2, CYP4AII, cytochrome P450 4A11, 20-HETE synthase, 20-hydroxyeicosatetraenoic acid synthase, CYPIVA11, P450HL-omega, alkane-1 monooxygenase, cytochrome P-450HK-omega, cytochrome P450, family 4, subfamily A, polypeptide 11, cytochrome P450, subfamily IVA, polypeptide 11, cytochrome P450HL-omega, fatty acid omega-hydroxylase, lauric acid omega-hydroxylase, long-chain fatty acid omega-monooxygenase
Genomic Location:
Chr 1: 47167433-47180004
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1p33





GO Molecular Function

cofactor binding | cation binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | arachidonic acid monooxygenase activity | tetrapyrrole binding | transition metal ion binding | alkane 1-monooxygenase activity | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | leukotriene-B4 20-monooxygenase activity | arachidonic acid epoxygenase activity

GO Biological Process

leukotriene metabolic process | regulation of localization | renal water homeostasis | regulation of lipid transport | cellular process | organic substance catabolic process | regulation of metabolic process | omega-hydroxylase P450 pathway | catabolic process | cellular lipid metabolic process | long-chain fatty acid catabolic process | monocarboxylic acid metabolic process | carboxylic acid catabolic process | multicellular organismal homeostasis | fatty acid catabolic process | blood circulation | metal ion homeostasis | water homeostasis | organic hydroxy compound metabolic process | sodium ion homeostasis | positive regulation of icosanoid secretion | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | positive regulation of secretion | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | regulation of blood pressure | regulation of systemic arterial blood pressure | pressure natriuresis | small molecule metabolic process | leukotriene B4 catabolic process | positive regulation of lipid localization | cation homeostasis | cellular lipid catabolic process | homeostatic process | positive regulation of transport | long-chain fatty acid metabolic process | arachidonic acid monooxygenase activity | carboxylic acid metabolic process | metabolic process | regulation of body fluid levels | oxidation-reduction process | chemical homeostasis | regulation of secretion | lipid catabolic process | organic substance metabolic process | positive regulation of ion transport | ion homeostasis | renal system process | fatty acid metabolic process | positive regulation of organic acid transport | icosanoid metabolic process | alkane 1-monooxygenase activity | organic acid metabolic process | epoxygenase P450 pathway | regulation of ion transport | renal system process involved in regulation of systemic arterial blood pressure | positive regulation of anion transport | regulation of transport | regulation of fatty acid transport | multicellular organismal water homeostasis | regulation of anion transport | regulation of lipid metabolic process | positive regulation of lipid transport | cellular metabolic process | oxidoreductase activity | arachidonic acid metabolic process | leukotriene-B4 20-monooxygenase activity | arachidonic acid epoxygenase activity | positive regulation of fatty acid transport | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | apical plasma membrane | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | apical part of cell | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane