QuickView for dsirt2;jsessionid=F67158940E90BADC7CE22F60D85A06EB;jsessionid=C99576B0E8F23D496149ED26D9FF1976 (gene)
- Gene Symbol:
- hst2
Schizosaccharomyces pombe - Full name:
- Sir2 family histone deacetylase Hst2
- Synonyms:
- SPCC132.02
- Genomic Location:
- Chr III: 1329098-1330220
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Danio rerio , Pan troglodytes , Bos taurus , Gallus gallus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | nucleotide binding | coenzyme binding | hydrolase activity | protein deacetylase activity | NAD+ binding | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | NAD-dependent protein deacetylase activity | anion binding | histone deacetylase activity | ion binding | organic cyclic compound binding | NAD-dependent histone deacetylase activity | zinc ion binding | NAD binding | transition metal ion binding | deacetylase activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of localization | nucleosome organization | negative regulation of cellular process | negative regulation of RNA biosynthetic process | histone modification | histone deacetylation | cellular process | regulation of gene expression, epigenetic | chromatin organization | negative regulation of nucleic acid-templated transcription | negative regulation of cellular metabolic process | regulation of cellular process | gene silencing | regulation of metabolic process | cellular component organization | negative regulation of metabolic process | protein modification process | protein deacetylase activity | macromolecule modification | histone H3 deacetylation | chromatin silencing at centromere outer repeat region | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | NAD-dependent protein deacetylase activity | regulation of transport by negative regulation of transcription from RNA polymerase II promoter | regulation of gene expression | histone deacetylase activity | negative regulation of gene expression, epigenetic | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | protein deacetylation | NAD-dependent histone deacetylase activity | regulation of cellular metabolic process | chromatin remodeling | histone H3-K9 deacetylation | regulation of RNA metabolic process | protein metabolic process | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | chromatin silencing at rDNA | covalent chromatin modification | regulation of transcription, DNA-templated | cellular protein metabolic process | regulation of nucleosome density | organelle organization | cellular protein modification process | negative regulation of transcription by RNA polymerase II | regulation of transport | chromatin silencing at centromere | chromosome organization | chromatin silencing | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
mating-type region heterochromatin | chromosome | intracellular membrane-bounded organelle | rDNA heterochromatin | subtelomeric heterochromatin | nuclear rDNA heterochromatin | chromosome, centromeric region | nuclear subtelomeric heterochromatin | cell | nuclear lumen | cytoplasm | intracellular organelle | chromatin | nuclear chromosome | pericentric heterochromatin | membrane-bounded organelle | heterochromatin | nucleus | organelle | nuclear heterochromatin | membrane-enclosed lumen | nuclear chromatin | cytosol | intracellular | nuclear pericentric heterochromatin
