QuickView for msh;jsessionid=0CA8E999077D7618AA8530E581A8ED6D;jsessionid=18AEF8FF7B59B43D87BB03420166B7A8 (gene)

Gene Symbol:

Pomc Mus musculus

Full name:

pro-opiomelanocortin-alpha

Synonyms:

ACTH, BE, Beta-LPH, Clip, Gamma-LPH, Npp, Pomc-1, Pomc1, alpha-MSH, alphaMSH, beta-MSH, gamma-MSH, pro-opiomelanocortin, adrenal corticotropic hormone, adrenocorticotropic hormone, alpha-melanocyte stimulating hormone, beta-endorphin, corticotropin-like intermediary peptide, corticotropin-lipotropin, melanotropin gamma, met-enkephalin

Genomic Location:

Chr 12: 3954951-3960618

Description:

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of thi...

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This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NKX25_02 ,  TATA_01 ,  NRSF_01 ,  STAT1_03 ,  TAATTA_CHX10_01 ,  CAGGTG_E12_Q6 ,  TGGAAA_NFAT_Q4_01

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