QuickView for nos;jsessionid=6DA7D49004DCF01D4EC872B52488708B;jsessionid=D8980894728F5226B8B9DFB4C85BCDFC (gene)
- Gene Symbol:
- NOS3
Bos taurus - Full name:
- nitric oxide synthase 3 (endothelial cell)
- Synonyms:
- N/A
- Genomic Location:
- Chr 4: 117855531-117873753
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
actin binding | NADP binding | cofactor binding | cation binding | carboxylic acid binding | ribonucleotide binding | FMN binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | carbohydrate derivative binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | cytoskeletal protein binding | anion binding | amino acid binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | scaffold protein binding | ion binding | organic cyclic compound binding | tetrahydrobiopterin binding | tetrapyrrole binding | protein binding | arginine binding | nitric-oxide synthase activity | heme binding | actin monomer binding | drug binding | calmodulin binding | organic acid binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
positive regulation of cyclase activity | smooth muscle hyperplasia | regulation of muscle system process | positive regulation of locomotion | regulation of systemic arterial blood pressure by hormone | cell motility | response to lipopolysaccharide | developmental process involved in reproduction | positive regulation of lyase activity | homeostasis of number of cells within a tissue | regulation of localization | regulation of the force of heart contraction by chemical signal | gonad development | regulation of programmed cell death | regulation of sodium ion transport | female gonad development | superoxide metabolic process | nitric oxide biosynthetic process | negative regulation of potassium ion transport | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | positive regulation of developmental process | respiratory tube development | reactive oxygen species metabolic process | epithelial cell migration | pulmonary valve development | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | mesenchyme development | tissue homeostasis | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular amino acid catabolic process | cellular process | organic substance catabolic process | regulation of cell motility | localization | cellular detoxification | tissue remodeling | heart morphogenesis | negative regulation of signaling | reproductive system development | epithelium migration | multicellular organismal reproductive process | hemostasis | negative regulation of apoptotic process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | tissue development | gamete generation | anatomical structure homeostasis | ventricular septum morphogenesis | negative regulation of apoptotic signaling pathway | cellular amino acid metabolic process | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | catabolic process | cellular response to molecule of bacterial origin | cellular component organization | regulation of systemic arterial blood pressure mediated by a chemical signal | positive regulation of epithelial cell migration | negative regulation of biomineral tissue development | development of primary sexual characteristics | regulation of vasculature development | response to stimulus | ovulation | vasculature development | female gamete generation | respiratory system development | blood vessel remodeling | negative regulation of cell adhesion | regulation of blood vessel size | carboxylic acid catabolic process | response to stress | endothelial cell migration | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | ovulation cycle | multicellular organismal homeostasis | response to laminar fluid shear stress | tube morphogenesis | regulation of blood circulation | development of primary female sexual characteristics | reproduction | cardiovascular system development | rhythmic process | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to toxic substance | regulation of guanylate cyclase activity | negative regulation of transport | positive regulation of blood vessel endothelial cell migration | blood circulation | reactive oxygen species biosynthetic process | regulation of cell adhesion | cellular biosynthetic process | embryo development | mitochondrion organization | ovulation from ovarian follicle | blood vessel development | pulmonary valve morphogenesis | blood coagulation | regulation of neurotransmitter levels | locomotion | endocardial cushion development | positive regulation of guanylate cyclase activity | response to external biotic stimulus | system development | removal of superoxide radicals | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | negative regulation of catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | cell migration | monooxygenase activity | regulation of catalytic activity | cellular response to oxidative stress | wound healing | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | response to lipid | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | regulation of blood pressure | endocardial cushion morphogenesis | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | animal organ morphogenesis | response to superoxide | regulation of nitrogen compound metabolic process | regulation of cell migration | small molecule metabolic process | negative regulation of muscle hyperplasia | cellular response to fluid shear stress | regulation of cellular component movement | response to oxidative stress | response to oxygen radical | regulation of the force of heart contraction | regulation of endothelial cell migration | negative regulation of extrinsic apoptotic signaling pathway | homeostasis of number of cells | neurotransmitter metabolic process | positive regulation of cell migration | biosynthetic process | aortic valve morphogenesis | angiogenesis | mesenchyme morphogenesis | negative regulation of ion transport | cardiac septum morphogenesis | response to toxic substance | regulation of systemic arterial blood pressure by endothelin | regulation of apoptotic signaling pathway | regulation of cyclase activity | regulation of heart contraction | ovulation cycle process | response to bacterium | negative regulation of cell-cell adhesion | chordate embryonic development | endocrine process | cell communication | regulation of cellular metabolic process | semi-lunar valve development | negative regulation of calcium ion transport | heart development | homeostatic process | arginine catabolic process | regulation of locomotion | embryo development ending in birth or egg hatching | lipopolysaccharide-mediated signaling pathway | regulation of tube size | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | coagulation | drug metabolic process | carboxylic acid metabolic process | regulation of potassium ion transport | positive regulation of molecular function | multicellular organism reproduction | reactive nitrogen species metabolic process | heart valve development | ventricular septum development | cardiac ventricle development | response to organic substance | tissue morphogenesis | nitric-oxide synthase activity | response to wounding | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cellular oxidant detoxification | regulation of body fluid levels | oxidation-reduction process | negative regulation of programmed cell death | cellular response to reactive oxygen species | heart valve morphogenesis | organic substance metabolic process | animal organ development | response to reactive oxygen species | regulation of phosphate metabolic process | positive regulation of endothelial cell migration | lung development | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | organonitrogen compound catabolic process | neurotransmitter biosynthetic process | response to fluid shear stress | regulation of cell communication | arginine metabolic process | regulation of blood vessel endothelial cell migration | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | organic acid metabolic process | anatomical structure morphogenesis | response to biotic stimulus | reproductive structure development | regulation of developmental process | regulation of ion transport | developmental process | organelle organization | nitric oxide metabolic process | regulation of calcium ion transport | cardiac septum development | tube development | regulation of transport | aortic valve development | negative regulation of cell proliferation | regulation of cell-cell adhesion | detoxification | smooth muscle adaptation | cardiac chamber development | negative regulation of hydrolase activity | cellular response to laminar fluid shear stress | cellular response to superoxide | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cell motility | oxidoreductase activity | negative regulation of cell death | circulatory system development | sexual reproduction | positive regulation of angiogenesis | muscle system process | response to other organism | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to lipopolysaccharide | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane microdomain | Golgi apparatus | endomembrane system | plasma membrane | membrane raft | membrane-bounded organelle | nucleus | organelle | cell periphery | plasma membrane raft | cytoskeleton | intracellular | caveola | membrane
