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QuickView for noxA;jsessionid=FAD4A50A75F7DFAC81816AB7BB61EF01;jsessionid=F64D335A027B8E0F332FCE4A4BE21088 (gene)


Gene Symbol:
Pmaip1 Mus musculus Mus musculus
Full name:
phorbol-12-myristate-13-acetate-induced protein 1
Synonyms:
Noxa, phorbol-12-myristate-13-acetate-induced protein 1, protein Noxa
Genomic Location:
Chr 18: 66618258-66625212
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_021451
Protein Names
Q9JM54



GO Molecular Function

protein binding

GO Biological Process

leukocyte homeostasis | response to radiation | regulation of cysteine-type endopeptidase activity | response to endoplasmic reticulum stress | release of cytochrome c from mitochondria | positive regulation of cellular component organization | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | response to X-ray | establishment of localization | negative regulation of cellular process | regulation of protein localization to membrane | intrinsic apoptotic signaling pathway in response to DNA damage | regulation of organelle organization | membrane organization | regulation of neuron death | negative regulation of mitochondrial membrane potential | cellular process | positive regulation of signal transduction by p53 class mediator | localization | regulation of DNA damage response, signal transduction by p53 class mediator | regulation of mitochondrial membrane potential | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of response to DNA damage stimulus | response to UV | response to stimulus | regulation of cellular protein localization | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | positive regulation of cellular protein localization | regulation of cell proliferation | positive regulation of cysteine-type endopeptidase activity | programmed cell death | positive regulation of proteolysis | apoptotic mitochondrial changes | mitochondrion organization | positive regulation of mitochondrion organization | regulation of membrane potential | regulation of cellular response to stress | apoptotic process | response to light stimulus | regulation of signal transduction | positive regulation of organelle organization | regulation of peptidase activity | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | cellular response to DNA damage stimulus | regulation of catalytic activity | positive regulation of DNA damage response, signal transduction by p53 class mediator | regulation of mitochondrial membrane permeability | cellular response to stress | regulation of signal transduction by p53 class mediator | positive regulation of cellular metabolic process | mitochondrial transport | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of intracellular signal transduction | positive regulation of hydrolase activity | homeostasis of number of cells | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | positive regulation of neuron death | regulation of apoptotic signaling pathway | negative regulation of membrane potential | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of mitochondrion organization | mitochondrial membrane organization | cell communication | regulation of cellular metabolic process | positive regulation of protein localization to membrane | regulation of neuron apoptotic process | lymphocyte homeostasis | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of establishment of protein localization | positive regulation of transport | apoptotic signaling pathway | positive regulation of molecular function | regulation of fibroblast proliferation | regulation of establishment of protein localization | regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | activation of cysteine-type endopeptidase activity involved in apoptotic process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | positive regulation of cell death | regulation of response to DNA damage stimulus | cell death | positive regulation of programmed cell death | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | intrinsic apoptotic signaling pathway by p53 class mediator | T cell homeostasis | regulation of cell communication | regulation of membrane permeability | signaling | negative regulation of fibroblast proliferation | regulation of endopeptidase activity | organelle organization | regulation of transport | negative regulation of cell proliferation | positive regulation of metabolic process | immune system process | regulation of protein localization | regulation of cell death | signal transduction by p53 class mediator | regulation of cellular component organization | response to ionizing radiation | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular