QuickView for pC2;jsessionid=9D2B93FA8217C790F4E6AF5C0BEFCA6A;jsessionid=B4317E42877B2986B0B4076593C6F59D (gene)

Gene Symbol:

Pcsk2 Rattus norvegicus

Full name:

proprotein convertase subtilisin/kexin type 2

Synonyms:

neuroendocrine convertase 2, KEX2-like endoprotease 2, NEC 2, PC2, prohormone convertase 2, proprotein convertase 2

Genomic Location:

Chr 3: 131925648-132256178

Description:

may play a role in endoproteolytic cleavage and processing of pro-choleycystokinin to produce CCK-8

may play a role in endoproteolytic cleavage and processing of pro-choleycystokinin to produce CCK-8

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Orthologs:

Homo sapiens ,  Mus musculus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CREBP1_01 ,  SOX5_01 ,  E4BP4_01 ,  NFKAPPAB65_01 ,  CREL_01 ,  NFKAPPAB_01 ,  CREB_02 ,  CEBPA_01 ,  OCT1_02 ,  NFKB_Q6 ,  NFKB_C ,  EGR1_01 ,  NGFIC_01 ,  NRSF_01 ,  HLF_01 ,  TCF11_01 ,  MEIS1BHOXA9_01 ,  NKX61_01 ,  SPZ1_01 ,  NKX3A_01 ,  STAT5A_01 ,  STAT5B_01 ,  STAT5A_02 ,  LHX3_01 ,  AFP1_Q6 ,  CEBPDELTA_Q6 ,  CDX2_Q5 ,  NFKB_Q6_01 ,  STAT_Q6 ,  GGAMTNNNNNTCCY_UNKNOWN ,  EGR_Q6 ,  GTGGGTGK_UNKNOWN ,  CATTTCA_MIR203 ,  ACCAAAG_MIR9 ,  RNGTGGGC_UNKNOWN ,  CACCAGC_MIR138 ,  TAATAAT_MIR126 ,  TGACATY_UNKNOWN ,  TGCGCANK_UNKNOWN ,  WTGAAAT_UNKNOWN ,  TGAYRTCA_ATF3_Q6 ,  TAATTA_CHX10_01 ,  TTAYRTAA_E4BP4_01 ,  GTGACGY_E4F1_Q6 ,  TGACCTY_ERR1_Q2 ,  TTGTTT_FOXO4_01 ,  TGTTTGY_HNF3_Q6 ,  CTTTGT_LEF1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  GCANCTGNY_MYOD_Q6 ,  GGGNNTTTCC_NFKB_Q6_01 ,  GGGTGGRR_PAX4_03 ,  CATTGTYY_SOX9_B1 ,  TTCYNRGAA_STAT5B_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-203

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