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QuickView for presenilin-1;jsessionid=8641E99C8940D3104E3396A8CCDDF0D0 (gene)


Gene Symbol:
psen1 Danio rerio Danio rerio
Full name:
presenilin
Synonyms:
pre1, psen, zf-PS1, zfPS1
Genomic Location:
Chr 17: 46696304-46712589
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_131024
Protein Names
Q9W6T7



GO Molecular Function

aspartic-type peptidase activity | hydrolase activity | catalytic activity | aspartic endopeptidase activity, intramembrane cleaving | aspartic-type endopeptidase activity | endopeptidase activity | peptidase activity

GO Biological Process

brain development | membrane protein proteolysis | Notch signaling pathway | proteolysis | amyloid-beta formation | protein processing | cell differentiation | nervous system development | cellular process | response to hypoxia | regulation of proteolysis | positive regulation of catalytic activity | lymphangiogenesis | regulation of canonical Wnt signaling pathway | tissue development | regulation of cellular process | regulation of metabolic process | aspartic-type peptidase activity | epithelium development | swimming behavior | head development | lymph vessel morphogenesis | response to stimulus | vasculature development | response to stress | membrane protein ectodomain proteolysis | pigment cell differentiation | cardiovascular system development | cellular nitrogen compound metabolic process | embryo development | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of peptidase activity | regulation of catalytic activity | lymph vessel development | developmental pigmentation | regulation of nitrogen compound metabolic process | cellular amide metabolic process | pigmentation | locomotory behavior | protein maturation | aspartic endopeptidase activity, intramembrane cleaving | cell communication | amyloid precursor protein catabolic process | regulation of protein metabolic process | peptide metabolic process | positive regulation of molecular function | protein metabolic process | aspartic-type endopeptidase activity | anatomical structure development | cell surface receptor signaling pathway | metabolic process | behavior | organic substance metabolic process | animal organ development | gene expression | regulation of Wnt signaling pathway | anatomical structure formation involved in morphogenesis | regulation of cell communication | signaling | somite development | endopeptidase activity | anatomical structure morphogenesis | regulation of endopeptidase activity | melanocyte differentiation | developmental process | amyloid-beta metabolic process | central nervous system development | cellular metabolic process | peptidase activity | circulatory system development | signal transduction | regulation of signaling | amyloid precursor protein metabolic process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | synapse | organelle membrane | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | gamma-secretase complex | intracellular organelle | endoplasmic reticulum | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | endomembrane system | endoplasmic reticulum membrane | plasma membrane | mitochondrion | integral component of plasma membrane | Golgi membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | cell junction | membrane | intrinsic component of plasma membrane