QuickView for ptenb;jsessionid=51744F4CE8F90055A54B2AAB7A349E06;jsessionid=B9E4F2646DF316ED4BD696DAE5730109;jsessionid=E633E99147FEDD2FAB02C0BCB86DA848 (gene)
- Gene Symbol:
- Pten
D. melanogaster - Full name:
- CG5671 gene product from transcript CG5671-RB
- Synonyms:
- CG5671, DmelCG5671, Dmel_CG5671, Dp110, DPTEN, PTEN, Pten, PTEN, PTEN3
- Genomic Location:
- Chr 2L: 10256318-10261017
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Danio rerio , Canis lupus familiaris , Gallus gallus , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , OCT1_01 , OCT1_04 , OCT1_05 , OCT1_Q6 , OCT_C , GFI1_01 , OCT1_B , POU3F2_02 , CEBPDELTA_Q6
GO Molecular Function
protein serine/threonine phosphatase activity | phosphatidylinositol bisphosphate phosphatase activity | actin binding | inositol phosphate phosphatase activity | phosphatase activity | protein tyrosine/serine/threonine phosphatase activity | phosphatidylinositol trisphosphate phosphatase activity | hydrolase activity | phosphatidylinositol monophosphate phosphatase activity | protein tyrosine phosphatase activity | catalytic activity | protein domain specific binding | cytoskeletal protein binding | phosphoprotein phosphatase activity | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | hydrolase activity, acting on ester bonds | phosphatidylinositol phosphate phosphatase activity | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | protein binding | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | phosphatidylinositol-3-phosphatase activity | phosphoric ester hydrolase activity | PDZ domain binding
GO Biological Process
protein serine/threonine phosphatase activity | negative regulation of TOR signaling | phosphatidylinositol bisphosphate phosphatase activity | response to extracellular stimulus | negative regulation of phosphorylation | negative regulation of phosphatidylinositol 3-kinase signaling | negative regulation of cellular response to insulin stimulus | response to nutrient levels | actin filament-based process | protein dephosphorylation | extracellular structure organization | regulation of cell morphogenesis | regulation of neurogenesis | developmental process involved in reproduction | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | larval midgut histolysis | regulation of localization | larval development | regulation of hemocyte proliferation | regulation of programmed cell death | eye development | phosphatidylinositol metabolic process | actin cytoskeleton organization | regulation of autophagy | regulation of immune system process | regulation of cell shape | negative regulation of cellular process | negative regulation of kinase activity | dendrite regeneration | cell differentiation | negative regulation of adherens junction organization | defense response | negative regulation of cell-matrix adhesion | negative regulation of organ growth | nervous system development | organophosphate catabolic process | negative regulation of protein phosphorylation | neurogenesis | polyol metabolic process | anatomical structure regression | generation of neurons | rhabdomere development | salivary gland morphogenesis | phospholipid metabolic process | phenol-containing compound metabolic process | melanin metabolic process | cellular process | organic substance catabolic process | regulation of cell motility | localization | negative regulation of signaling | negative regulation of axon regeneration | neuron development | negative regulation of developmental growth | multicellular organismal reproductive process | macromolecule localization | regulation of cell cycle | regulation of multicellular organism growth | negative regulation of cell migration | regulation of neuron projection development | negative regulation of cellular metabolic process | tissue development | negative regulation of lipid kinase activity | regulation of cell differentiation | gamete generation | muscle structure development | inositol phosphate catabolic process | regeneration | negative regulation of cell motility | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | phosphorylated carbohydrate dephosphorylation | organic cyclic compound metabolic process | basement membrane organization | epithelium development | cellular aromatic compound metabolic process | regulation of establishment of planar polarity | inositol phosphate phosphatase activity | cellular component organization | cellular lipid metabolic process | cell competition in a multicellular organism | phosphatase activity | response to stimulus | protein tyrosine/serine/threonine phosphatase activity | female gamete generation | phosphatidylinositol trisphosphate phosphatase activity | respiratory system development | metamorphosis | negative regulation of cell adhesion | melanotic encapsulation of foreign target | gland morphogenesis | response to stress | germ cell development | negative regulation of protein kinase activity | alcohol metabolic process | regulation of cell proliferation | negative regulation of neuron projection development | epithelial cell development | response to starvation | phosphatidylinositol monophosphate phosphatase activity | reproduction | cellular localization | compound eye photoreceptor development | instar larval or pupal development | regulation of neuron projection regeneration | extracellular matrix organization | negative regulation of metabolic process | regulation of cellular component size | protein modification process | regulation of cell adhesion | regulation of phosphatidylinositol 3-kinase activity | macromolecule modification | regulation of lipid storage | regulation of TOR signaling | protein tyrosine phosphatase activity | eye photoreceptor cell differentiation | regulation of cellular response to stress | organic hydroxy compound metabolic process | protein kinase B signaling | system development | nitrogen compound metabolic process | alcohol catabolic process | reproductive process | regulation of signal transduction | negative regulation of growth | regulation of protein stability | negative regulation of phosphate metabolic process | regulation of adherens junction organization | multicellular organism development | negative regulation of catalytic activity | phosphorus metabolic process | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | regulation of neuron differentiation | regulation of TORC1 signaling | cellular response to stress | organophosphate metabolic process | negative regulation of lipid storage | animal organ morphogenesis | phosphoprotein phosphatase activity | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | small molecule metabolic process | negative regulation of insulin receptor signaling pathway | cellular carbohydrate metabolic process | post-embryonic animal morphogenesis | regulation of cellular component movement | oogenesis | open tracheal system development | melanization defense response | cell proliferation | negative regulation of protein kinase B signaling | neuron projection regeneration | regulation of cellular protein metabolic process | inositol phosphate dephosphorylation | negative regulation of cell-substrate adhesion | negative regulation of multicellular organism growth | carbohydrate metabolic process | phosphatidylinositol phosphate phosphatase activity | compound eye morphogenesis | instar larval development | post-embryonic development | phosphate-containing compound metabolic process | sensory organ development | autophagy | negative regulation of response to wounding | regulation of lipid kinase activity | compound eye development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | eye morphogenesis | regulation of protein metabolic process | lipid modification | homeostatic process | regulation of protein phosphorylation | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | regulation of locomotion | glycerolipid metabolic process | eye photoreceptor cell development | regulation of phospholipid metabolic process | negative regulation of cell growth | neuron differentiation | multicellular organism reproduction | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | protein metabolic process | regulation of growth | gland development | negative regulation of cell projection organization | ovarian follicle cell development | phosphatidylinositol dephosphorylation | regulation of kinase activity | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | phosphatidylinositol-3-phosphatase activity | regulation of focal adhesion assembly | anatomical structure development | negative regulation of lipid metabolic process | cell projection organization | metabolic process | cell fate commitment | somatic muscle development | negative regulation of cell size | cellular protein localization | chemical homeostasis | positive regulation of cell death | immune response | compound eye photoreceptor cell differentiation | neuron projection development | organic substance metabolic process | pigment metabolic process | animal organ development | negative regulation of neuron differentiation | regulation of insulin receptor signaling pathway | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | positive regulation of programmed cell death | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | cytoskeleton organization | negative regulation of TORC1 signaling | regulation of axon regeneration | negative regulation of protein metabolic process | regulation of dendrite development | regulation of response to wounding | regulation of cell communication | dephosphorylation | negative regulation of molecular function | negative regulation of signal transduction | signaling | cell development | regulation of developmental growth | protein localization | cellular protein metabolic process | regulation of cell size | anatomical structure morphogenesis | cellular macromolecule localization | regulation of organ growth | dendrite development | regulation of nervous system development | regulation of developmental process | negative regulation of neuron projection regeneration | glycerophospholipid metabolic process | developmental process | organelle organization | larval salivary gland morphogenesis | regulation of cell growth | cellular protein modification process | negative regulation of focal adhesion assembly | columnar/cuboidal epithelial cell development | regulation of cell junction assembly | negative regulation of cell proliferation | peptidyl-tyrosine dephosphorylation | innate immune response | cell fate determination | photoreceptor cell development | epithelial cell differentiation | negative regulation of phosphatidylinositol 3-kinase activity | regulation of lipid metabolic process | phospholipid dephosphorylation | regulation of cell projection organization | immune system process | cellular metabolic process | photoreceptor cell differentiation | exocrine system development | regulation of cell death | salivary gland development | negative regulation of cell development | negative regulation of locomotion | sexual reproduction | lipid homeostasis | negative regulation of cell differentiation | regulation of cellular component organization | inositol phosphate metabolic process | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | epithelial cell fate determination, open tracheal system | encapsulation of foreign target | regulation of cell-matrix adhesion | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
