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QuickView for rsks-1;jsessionid=64A8880BB40D1C85DED69B1D13753F1C;jsessionid=905A092E3E8B4F65040E125102FBBC1C (gene)


Gene Symbol:
Rps6kb1 Rattus norvegicus Rattus norvegicus
Full name:
ribosomal protein S6 kinase B1
Synonyms:
p70 S6K-alpha, ribosomal protein S6 kinase beta-1, 70 kDa ribosomal protein S6 kinase 1, P70S6K, P70S6K1, S6 kinase, S6K, S6K-beta-1, S6K1, p70 S6 kinase alpha, p70 S6KA, p70 ribosomal S6 kinase alpha, p70(S6K)-alpha, p70-S6K 1, ribosomal protein S6 kinase I, ribosomal protein S6 kinase, 70kDa, polypeptide 1, ribosomal protein S6 kinase, polypeptide 1
Genomic Location:
Chr 10: 76657024-76698088
Description:
may play a role in response to oxidative stress
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
GATA1_01 EVI1_04 HFH1_01 FOXD3_01 OCT1_03 AP4_Q5 AP4_Q6 GFI1_01 OLF1_01 LMO2COM_01
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-128 Predicted Gene Targets for miR-129 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-142-5p Predicted Gene Targets for miR-145 Predicted Gene Targets for miR-153 Predicted Gene Targets for miR-181 Predicted Gene Targets for miR-186 Predicted Gene Targets for miR-189 Predicted Gene Targets for miR-199


Protein Names
P21425
P67999



GO Molecular Function

peptide binding | protein phosphatase 2A binding | enzyme binding | ribonucleotide binding | ribosomal protein S6 kinase activity | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | amide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein phosphatase binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | PDZ domain binding | adenyl ribonucleotide binding | protein serine/threonine/tyrosine kinase activity | drug binding | kinase activity | phosphatase binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of smooth muscle cell proliferation | response to extracellular stimulus | multicellular organismal movement | long-chain fatty acid transport | regulation of muscle system process | negative regulation of cellular response to insulin stimulus | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to nutrient levels | long-term memory | response to cytokine | cell motility | behavioral fear response | response to lipopolysaccharide | developmental process involved in reproduction | intracellular signal transduction | positive regulation of skeletal muscle tissue development | regulation of localization | positive regulation of striated muscle tissue development | lipid transport | regulation of programmed cell death | peptidyl-amino acid modification | establishment of localization | response to hormone | negative regulation of cellular process | positive regulation of developmental process | response to dexamethasone | cell differentiation | defense response | response to drug | positive regulation of cellular component movement | striated muscle atrophy | response to antibiotic | positive regulation of cellular biosynthetic process | cellular process | musculoskeletal movement | monocarboxylic acid transport | regulation of glucose import | regulation of cell motility | localization | negative regulation of signaling | TOR signaling | anion transport | multicellular organismal reproductive process | response to leucine | regulation of striated muscle tissue development | macromolecule localization | negative regulation of apoptotic process | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | response to peptide hormone | gamete generation | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | ribosomal protein S6 kinase activity | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular response to interferon-gamma | regulation of translational initiation | muscle contraction | response to stimulus | positive regulation of protein metabolic process | cellular response to xenobiotic stimulus | response to stress | regulation of skeletal muscle tissue growth | germ cell development | posttranscriptional regulation of gene expression | regulation of cell proliferation | response to peptide | response to glucose | regulation of smooth muscle cell migration | protein serine/threonine kinase activity | programmed cell death | reproduction | response to alcohol | response to temperature stimulus | response to molecule of bacterial origin | cell cycle G1/S phase transition | cellular response to organic cyclic compound | protein modification process | macromolecule modification | response to ethanol | locomotion | response to nitrogen compound | apoptotic process | protein kinase B signaling | cellular response to hormone stimulus | regulation of skeletal muscle tissue development | response to external biotic stimulus | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | cell migration | cellular response to peptide hormone stimulus | phosphorus metabolic process | response to amino acid | learning or memory | positive regulation of smooth muscle cell migration | positive regulation of muscle organ development | cellular response to insulin stimulus | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | fatty acid transport | organic substance transport | response to ketone | response to lipid | nervous system process | cellular response to peptide | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cell migration | negative regulation of insulin receptor signaling pathway | response to corticosteroid | regulation of cellular component movement | response to nutrient | organic acid transport | negative regulation of extrinsic apoptotic signaling pathway | cognition | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | cellular response to glucocorticoid stimulus | organic anion transport | phosphorylation | response to toxic substance | regulation of apoptotic signaling pathway | response to xenobiotic stimulus | mitotic cell cycle phase transition | protein phosphorylation | cellular response to corticosteroid stimulus | phosphate-containing compound metabolic process | cellular response to drug | response to bacterium | cell communication | regulation of cellular metabolic process | skeletal muscle atrophy | response to testosterone | regulation of protein metabolic process | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | response to monosaccharide | regulation of locomotion | striated muscle contraction | regulation of mitotic cell cycle | positive regulation of translational initiation | multicellular organism reproduction | response to glucagon | multicellular organismal response to stress | fear response | protein metabolic process | skeletal muscle adaptation | regulation of growth | response to organic substance | response to wounding | response to antineoplastic agent | response to mechanical stimulus | response to insulin | anatomical structure development | mitotic cell cycle | positive regulation of skeletal muscle tissue growth | metabolic process | lipid localization | negative regulation of programmed cell death | response to electrical stimulus involved in regulation of muscle adaptation | behavior | immune response | protein kinase activity | organic substance metabolic process | cell death | regulation of glucose transmembrane transport | long-chain fatty acid import | regulation of insulin receptor signaling pathway | muscle atrophy | response to heat | regulation of cellular response to insulin stimulus | cellular response to steroid hormone stimulus | positive regulation of muscle tissue development | response to interferon-gamma | cellular response to dexamethasone stimulus | memory | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | response to organic cyclic compound | cell development | skeletal muscle contraction | regulation of developmental growth | cellular protein metabolic process | carboxylic acid transport | protein serine/threonine/tyrosine kinase activity | response to biotic stimulus | regulation of developmental process | kinase activity | developmental process | behavioral defense response | peptidyl-serine phosphorylation | cellular protein modification process | regulation of transport | innate immune response | response to organonitrogen compound | cell cycle phase transition | response to electrical stimulus | positive regulation of metabolic process | ion transport | immune system process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of cell motility | response to carbohydrate | response to steroid hormone | regulation of translation | negative regulation of cell death | aging | sexual reproduction | muscle system process | response to other organism | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | synapse | neuron projection | organelle membrane | cell | organelle outer membrane | nuclear lumen | cytoplasm | intracellular organelle | cell projection | nucleoplasm | perinuclear region of cytoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | membrane-enclosed lumen | outer membrane | mitochondrial membrane | cytosol | cell surface | intracellular | cell junction | membrane