QuickView for scrA;jsessionid=0914A62826584B9D584508645F482CEA;jsessionid=BC52834117BAA1D4753738F8603F0617 (gene)

Gene Symbol:

ANLN Homo sapiens

Full name:

anillin actin binding protein

Synonyms:

FSGS8, Scraps, scra, anillin, actin-binding protein anillin

Genomic Location:

Chr 7: 36395957-36459925

Description:

This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple tr...

View Full Description

This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

WGTTNNNNNAAA_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  NKX25_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  BRN2_01 ,  TATTATA_MIR374

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-217 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

7p14.2

search → result