QuickView for ship;jsessionid=5F4A6481CF8F4F7C186AC9BEC4F0BCF6;jsessionid=11AF4111CFA4C7DBAFE94B3DCCBD3182;jsessionid=F8470378FAD32F8DB353ED273E3EE459 (gene)
- Gene Symbol:
- Inpp5d
Mus musculus - Full name:
- inositol polyphosphate-5-phosphatase D
- Synonyms:
- SHIP, SHIP-1, SHIP1, SIP-145, p150Ship, s-SHIP, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, SH2 domain-containing inositol 5'-phosphatase 1, SH2 domain-containing inositol phosphatase 1, SH2-containing inositol phosphatase SHIP, Src homology 2 domain-containing inositol-5-phosphatase, inositol polyphosphate-5-phosphatase, 145 kDa
- Genomic Location:
- Chr 1: 89516954-89617077
- Orthologs:
- Homo sapiens , Rattus norvegicus , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
inositol-4,5-bisphosphate 5-phosphatase activity | inositol-polyphosphate 5-phosphatase activity | PTB domain binding | SH3 domain binding | inositol phosphate phosphatase activity | phosphatase activity | phosphatidylinositol trisphosphate phosphatase activity | hydrolase activity | catalytic activity | inositol bisphosphate phosphatase activity | protein domain specific binding | hydrolase activity, acting on ester bonds | inositol trisphosphate phosphatase activity | phosphatidylinositol phosphate phosphatase activity | protein binding | phosphoric ester hydrolase activity
GO Biological Process
negative regulation of leukocyte activation | positive regulation of erythrocyte differentiation | adaptive immune response | negative regulation of immune system process | regulation of monocyte differentiation | regulation of B cell activation | intracellular signal transduction | positive regulation of apoptotic process | regulation of programmed cell death | inositol-4,5-bisphosphate 5-phosphatase activity | phosphatidylinositol metabolic process | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of lymphocyte activation | negative regulation of tissue remodeling | negative regulation of neutrophil differentiation | negative regulation of B cell proliferation | negative regulation of osteoclast differentiation | inositol-polyphosphate 5-phosphatase activity | phospholipid metabolic process | regulation of bone remodeling | cellular process | regulation of cytokine biosynthetic process | negative regulation of signaling | regulation of myeloid cell differentiation | negative regulation of cellular metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | negative regulation of granulocyte differentiation | negative regulation of mononuclear cell proliferation | negative regulation of bone resorption | inositol phosphate phosphatase activity | cellular lipid metabolic process | phosphatase activity | response to stimulus | phosphatidylinositol trisphosphate phosphatase activity | positive regulation of immune system process | negative regulation of lymphocyte activation | regulation of cell proliferation | regulation of granulocyte differentiation | negative regulation of interleukin-6 biosynthetic process | programmed cell death | positive regulation of cell activation | negative regulation of metabolic process | negative regulation of hemopoiesis | positive regulation of B cell differentiation | regulation of lymphocyte differentiation | inositol bisphosphate phosphatase activity | apoptotic process | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | regulation of signal transduction | negative regulation of interleukin-6 production | multicellular organism development | positive regulation of lymphocyte differentiation | phosphorus metabolic process | regulation of neutrophil differentiation | leukocyte mediated immunity | lipid metabolic process | organophosphate metabolic process | negative regulation of cytokine production | regulation of lymphocyte activation | negative regulation of myeloid cell differentiation | regulation of nitrogen compound metabolic process | regulation of interleukin-6 biosynthetic process | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | inositol trisphosphate phosphatase activity | negative regulation of immune response | phosphatidylinositol phosphate phosphatase activity | phosphate-containing compound metabolic process | negative regulation of cytokine biosynthetic process | cell communication | regulation of cellular metabolic process | negative regulation of cell activation | regulation of protein metabolic process | lipid modification | glycerolipid metabolic process | positive regulation of B cell activation | negative regulation of B cell activation | regulation of hemopoiesis | phosphatidylinositol dephosphorylation | anatomical structure development | metabolic process | negative regulation of leukocyte proliferation | positive regulation of leukocyte activation | regulation of bone resorption | regulation of erythrocyte differentiation | regulation of tissue remodeling | positive regulation of cell death | immune response | organic substance metabolic process | regulation of B cell differentiation | cell death | negative regulation of biosynthetic process | regulation of cell activation | positive regulation of programmed cell death | negative regulation of protein metabolic process | regulation of osteoclast differentiation | multicellular organism aging | regulation of cell communication | dephosphorylation | negative regulation of signal transduction | signaling | determination of adult lifespan | regulation of cytokine production | negative regulation of monocyte differentiation | regulation of developmental process | B cell mediated immunity | glycerophospholipid metabolic process | developmental process | regulation of B cell proliferation | negative regulation of cell proliferation | negative regulation of bone remodeling | phospholipid dephosphorylation | negative regulation of lymphocyte proliferation | immunoglobulin mediated immune response | immune system process | cellular metabolic process | regulation of cell death | regulation of interleukin-6 production | aging | negative regulation of myeloid leukocyte differentiation | negative regulation of cell differentiation | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
supramolecular fiber | cell | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | plasma membrane | cytoplasmic region | cell cortex | organelle | cell periphery | cytosol | actin filament | cytoskeleton | intracellular | membrane | supramolecular complex
