QuickView for smc6;jsessionid=E6055866E5BDAB92E2BB9D947E367592;jsessionid=8F1CAE3197FD8AE36F91AF858BF0890D (gene)
- Gene Symbol:
- SMC6
Saccharomyces cerevisiae - Full name:
- Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18
- Synonyms:
- RHC18, SMC6, YLR383W
- Genomic Location:
- Chr XII: 885288-888632
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
nucleic acid binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | ubiquitin-like protein transferase activity | anion binding | adenyl nucleotide binding | DNA binding | purine nucleotide binding | damaged DNA binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | SUMO transferase activity | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
double-strand break repair | DNA double-strand break attachment to nuclear envelope | peptidyl-amino acid modification | protein sumoylation | resolution of recombination intermediates | cellular process | localization | organelle localization | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | chromosome segregation | response to stress | cellular localization | cellular nitrogen compound metabolic process | protein modification process | DNA recombination | macromolecule modification | DNA repair | nitrogen compound metabolic process | double-strand break repair via homologous recombination | cellular response to DNA damage stimulus | cellular response to stress | cell cycle | protein modification by small protein conjugation | protein metabolic process | DNA metabolic process | metabolic process | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | cellular protein metabolic process | SUMO transferase activity | recombinational repair | cellular protein modification process | heterocycle metabolic process | chromosome attachment to the nuclear envelope | cellular metabolic process | chromosome separation | macromolecule metabolic process
GO Cellular Component
site of DNA damage | chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | cytoplasm | intracellular organelle | protein-containing complex | transferase complex | mitochondrion | Smc5-Smc6 complex | site of double-strand break | membrane-bounded organelle | nucleus | organelle | intracellular | condensed chromosome
