QuickView for spastin;jsessionid=35B104413BB1A6BFDF0405A4F5750D69;jsessionid=6A5B0060C9CCB7438E6F9FCA58D1772D (gene)
- Gene Symbol:
- Spast
Rattus norvegicus - Full name:
- spastin
- Synonyms:
- Spg4, spastin, spastic paraplegia 4 (autosomal dominant, spastic paraplegia 4 (autosomal dominant; spastin)
- Genomic Location:
- Chr 6: 20990783-21049095
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-186 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-30 , Predicted Gene Targets for miR-96 , Predicted Gene Targets for miR-203 , Predicted Gene Targets for miR-29 , Predicted Gene Targets for miR-486 , Predicted Gene Targets for miR-495 , Predicted Gene Targets for miR-496
GO Molecular Function
alpha-tubulin binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | beta-tubulin binding | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | microtubule binding | microtubule-severing ATPase activity | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
mitotic cytokinesis | regulation of supramolecular fiber organization | protein homooligomerization | cell morphogenesis | nucleus organization | protein hexamerization | regulation of cell cycle process | microtubule-based transport | microtubule cytoskeleton organization involved in mitosis | regulation of microtubule polymerization or depolymerization | positive regulation of cellular component organization | neuron projection morphogenesis | microtubule bundle formation | establishment of localization | microtubule cytoskeleton organization | cell differentiation | nervous system development | cell part morphogenesis | neurogenesis | regulation of organelle organization | generation of neurons | membrane organization | intracellular transport | microtubule-based process | cellular process | establishment of organelle localization | localization | cell projection morphogenesis | cytokinetic process | neuron development | cytoskeleton-dependent cytokinesis | endomembrane system organization | regulation of cell cycle | positive regulation of cell division | establishment of localization in cell | positive regulation of cytokinesis | cytoskeleton-dependent intracellular transport | regulation of cellular process | organelle localization | positive regulation of protein complex disassembly | cellular component organization | regulation of cell division | regulation of microtubule depolymerization | cell morphogenesis involved in neuron differentiation | nuclear envelope reassembly | mitotic spindle organization | organelle transport along microtubule | supramolecular fiber organization | exit from mitosis | microtubule-based movement | cellular localization | nuclear envelope organization | cellular component assembly | mitochondrion transport along microtubule | system development | positive regulation of organelle organization | multicellular organism development | protein complex oligomerization | regulation of protein complex disassembly | positive regulation of cell cycle | axon development | cell cycle | membrane fission | vesicle-mediated transport | positive regulation of protein depolymerization | axonogenesis | mitochondrion localization | cell division | cytokinesis | mitotic cell cycle phase transition | cell morphogenesis involved in differentiation | regulation of cytokinesis | anterograde axonal transport | cytoplasmic microtubule organization | positive regulation of cytoskeleton organization | Golgi vesicle transport | regulation of protein depolymerization | microtubule severing | regulation of microtubule-based process | organelle disassembly | neuron differentiation | protein-containing complex assembly | establishment of mitochondrion localization, microtubule-mediated | establishment of mitochondrion localization | anatomical structure development | mitotic cell cycle | nuclear division | cell projection organization | positive regulation of supramolecular fiber organization | transport along microtubule | neuron projection development | cytoskeleton organization | mitotic nuclear division | microtubule-severing ATPase activity | axo-dendritic transport | ER to Golgi vesicle-mediated transport | cell development | anatomical structure morphogenesis | developmental process | axonal transport of mitochondrion | organelle organization | positive regulation of cell cycle process | cell cycle phase transition | positive regulation of microtubule depolymerization | spindle organization | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | axonal transport | mitotic spindle disassembly | regulation of cytoskeleton organization | multicellular organismal process
GO Cellular Component
supramolecular fiber | integral component of membrane | intracellular membrane-bounded organelle | neuron projection | organelle membrane | microtubule organizing center | nuclear membrane | cytoplasmic vesicle | cell | nuclear lumen | intrinsic component of membrane | microtubule | cytoplasm | spindle | intracellular organelle | endoplasmic reticulum | centrosome | cell projection | endomembrane system | nucleoplasm | plasma membrane bounded cell projection cytoplasm | nuclear envelope | midbody | vesicle | perinuclear region of cytoplasm | microtubule cytoskeleton | cytoplasmic region | endosome | membrane-bounded organelle | nucleus | organelle | axon cytoplasm | axon | membrane-enclosed lumen | endoplasmic reticulum tubular network | cytosol | intracellular vesicle | cytoskeleton | intracellular | membrane | supramolecular complex
