QuickView for tagL;jsessionid=966C4809A581F4B75FD22D1010F3E9CB;jsessionid=257684F3971D4FF99BC797E1155889A7 (gene)
- Gene Symbol:
- PGRP-LB
D. melanogaster - Full name:
- Peptidoglycan recognition protein LB
- Synonyms:
- CG14704, DmelCG14704, Dmel_CG14704, PGRP-LB
- Genomic Location:
- Chr 3R: 7278563-7283742
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
N-acetylmuramoyl-L-alanine amidase activity | cation binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | peptidoglycan receptor activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | signaling receptor activity | ion binding | signaling pattern recognition receptor activity | protein binding | peptidoglycan binding | zinc ion binding | glycosaminoglycan binding | transition metal ion binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | metal ion binding | amidase activity
GO Biological Process
positive regulation of immune response | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | negative regulation of immune system process | immune response-regulating signaling pathway | defense response to other organism | regulation of immune system process | negative regulation of cellular process | defense response | peptidoglycan catabolic process | innate immune response-activating signal transduction | cellular process | organic substance catabolic process | negative regulation of signaling | carbohydrate derivative catabolic process | glycosaminoglycan catabolic process | regulation of cell differentiation | regulation of immune response | regulation of cellular process | catabolic process | regulation of natural killer cell activation | response to stimulus | positive regulation of innate immune response | positive regulation of immune system process | response to stress | negative regulation of lymphocyte activation | activation of innate immune response | negative regulation of peptidoglycan recognition protein signaling pathway | immune response-activating signal transduction | negative regulation of hemopoiesis | regulation of lymphocyte differentiation | peptidoglycan receptor activity | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | pattern recognition receptor signaling pathway | regulation of lymphocyte activation | regulation of defense response to bacterium | negative regulation of immune response | peptidoglycan metabolic process | response to bacterium | cell communication | negative regulation of natural killer cell differentiation involved in immune response | signaling pattern recognition receptor activity | negative regulation of cell activation | humoral immune response | defense response to bacterium | negative regulation of natural killer cell activation | antimicrobial humoral response | regulation of natural killer cell differentiation involved in immune response | activation of immune response | regulation of innate immune response | regulation of hemopoiesis | metabolic process | immune response | organic substance metabolic process | regulation of cell activation | organonitrogen compound catabolic process | regulation of natural killer cell differentiation | defense response to Gram-positive bacterium | regulation of cell communication | negative regulation of signal transduction | signaling | response to biotic stimulus | regulation of developmental process | negative regulation of defense response to bacterium | carbohydrate derivative metabolic process | innate immune response | immune system process | negative regulation of cell differentiation | response to other organism | signal transduction | regulation of signaling | glycosaminoglycan metabolic process | macromolecule metabolic process
