QuickView for tok-like;jsessionid=7A4436064AE98E3D41C1FA80704B44C4;jsessionid=6E8425E77C83347EF18997CF8C460867 (gene)
- Gene Symbol:
- Cubn
Rattus norvegicus - Full name:
- cubilin
- Synonyms:
- GP280, IFCR, MGA1, cubilin, 460 kDa receptor, glycoprotein 280, intrinsic factor-cobalamin receptor, intrinsic factor-vitamin B12 receptor
- Genomic Location:
- Chr 17: 87545893-87772079
- Description:
-
receptor for intrinsic factor (IF)-cobalamin; involved in vitamin B12 uptake (cyanocobalamin)
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Canis lupus familiaris , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | channel regulator activity | cation binding | hemoglobin binding | vitamin binding | molecular function regulator | signaling receptor activity | identical protein binding | ion binding | organic cyclic compound binding | tetrapyrrole binding | protein binding | protein homodimerization activity | protein dimerization activity | cobalamin binding | calcium ion binding | drug binding | metal ion binding | heterocyclic compound binding | cargo receptor activity | small molecule binding
GO Biological Process
response to extracellular stimulus | protein homooligomerization | response to nutrient levels | hyperosmotic response | cobalamin metabolic process | cell-cell signaling involved in cell fate commitment | establishment of localization | cell differentiation | response to drug | sterol metabolic process | cellular process | organic substance catabolic process | channel regulator activity | localization | positive regulation of synaptic transmission | protein transport | macromolecule localization | regulation of cellular process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | response to stress | alcohol metabolic process | protein homotrimerization | cellular localization | cellular nitrogen compound metabolic process | lipoprotein transport | cofactor metabolic process | cellular component assembly | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | embryo development | cell-cell signaling | drug catabolic process | molecular function regulator | locomotion | organic hydroxy compound metabolic process | response to external biotic stimulus | nitrogen compound metabolic process | multicellular organism development | thigmotaxis | regulation of synaptic transmission, glutamatergic | endocytic hemoglobin import | protein complex oligomerization | vitamin transport | lipid metabolic process | organic substance transport | adult locomotory behavior | small molecule metabolic process | peptide transport | vesicle-mediated transport | cobalamin catabolic process | response to nutrient | protein localization to organelle | locomotory behavior | response to osmotic stress | protein import | response to bacterium | chordate embryonic development | cell communication | protein trimerization | aromatic compound catabolic process | regulation of locomotion | embryo development ending in birth or egg hatching | drug metabolic process | protein-containing complex assembly | vitamin metabolic process | import into cell | establishment of protein localization to organelle | anatomical structure development | cofactor transport | lateral inhibition | metabolic process | cell fate commitment | cholesterol metabolic process | cellular protein localization | amide transport | endocytosis | behavior | organic substance metabolic process | establishment of protein localization | drug transport | adult behavior | organonitrogen compound catabolic process | steroid metabolic process | regulation of cell communication | cobalamin transport | signaling | protein localization | cellular macromolecule localization | response to biotic stimulus | heme transport | receptor-mediated endocytosis | developmental process | heterocycle metabolic process | in utero embryonic development | cargo receptor activity | cellular metabolic process | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
brush border | integral component of membrane | intracellular membrane-bounded organelle | synapse | apical plasma membrane | neuron projection | endocytic vesicle membrane | organelle membrane | cell projection membrane | cytoplasmic vesicle | cell | plasma membrane protein complex | vacuolar lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | brush border membrane | leading edge membrane | apical part of cell | endosome membrane | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | Golgi-associated vesicle | cell leading edge | vacuole | vesicle | clathrin-coated pit | extracellular exosome | lytic vacuole | integral component of plasma membrane | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | lysosome | extracellular space | cell periphery | membrane-enclosed lumen | ionotropic glutamate receptor complex | lysosomal lumen | transmembrane transporter complex | ion channel complex | intracellular vesicle | endocytic vesicle | intracellular | lysosomal membrane | membrane | cytoplasmic vesicle membrane | neuron projection membrane | intrinsic component of plasma membrane | vacuolar membrane | coated vesicle
