QuickView for torsinB;jsessionid=F494171E3B0A38C8BAB39186029410A7;jsessionid=5F38F57043F088273BF26587D864DDC6 (gene)
- Gene Symbol:
- TOR1B
Homo sapiens - Full name:
- torsin family 1 member B
- Synonyms:
- DQ1, torsin-1B, torsin ATPase-1B, torsin B
- Genomic Location:
- Chr 9: 131605253-131613381
- Description:
-
The protein encoded by this gene is an ATPase found primarily in the endoplasmic reticulum and nuclear envelope. This gene has a highly-similar neighboring gene, TOR1A, that encodes a protein that is likely to interact in a complex with this protein. Finally, this protein may act as a chaperone and play a role in maintaining the integrity of the nu...
- Orthologs:
- Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
9q34.11
| Transcripts Names |
|---|
| NM_014506 |
| XM_005251927 |
| NR_134113 |
| NM_001317894 |
| NR_134027 |
| NR_133948 |
| XR_001746273 |
| NM_001317893 |
GO Molecular Function
ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
protein homooligomerization | nucleus organization | 'de novo' posttranslational protein folding | membrane organization | cellular process | chaperone-mediated protein folding | endomembrane system organization | response to topologically incorrect protein | cellular component organization | response to stimulus | response to stress | nuclear envelope organization | cellular component assembly | protein complex oligomerization | 'de novo' protein folding | nuclear membrane organization | protein-containing complex assembly | response to organic substance | protein folding | response to unfolded protein | chaperone cofactor-dependent protein refolding | organelle organization | endoplasmic reticulum organization
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | endomembrane system | nuclear envelope | vesicle | endoplasmic reticulum lumen | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | intracellular | membrane
