QuickView for zonulin;jsessionid=02FF1AFB75DD86BAC1E6D9C61A78D26D;jsessionid=2158C74AA878EE51CA5E379A51F8F15A (gene)
- Gene Symbol:
- Hp
Rattus norvegicus - Full name:
- haptoglobin
- Synonyms:
- Ba1-647, haptoglobin, liver regeneration-related protein LRRG173, zonulin
- Genomic Location:
- Chr 19: 39443016-39447566
- Description:
-
may bind hemoglobin and mediate hemoglobin catabolism in lung cells; may play a role in inflammatory response
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
antioxidant activity | hemoglobin binding | hydrolase activity | catalytic activity | serine hydrolase activity | identical protein binding | protein binding | protein homodimerization activity | protein dimerization activity | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | peptidase activity
GO Biological Process
response to extracellular stimulus | Notch signaling pathway | response to radiation | response to nutrient levels | response to lipopolysaccharide | proteolysis | response to X-ray | defense response to other organism | response to hormone | negative regulation of cellular process | response to metal ion | male gamete generation | defense response | response to growth hormone | response to drug | response to antibiotic | cellular process | response to magnesium ion | cellular detoxification | antioxidant activity | multicellular organismal reproductive process | response to hypoxia | negative regulation of hydrogen peroxide catabolic process | response to inorganic substance | negative regulation of cellular metabolic process | response to peptide hormone | gamete generation | response to cobalamin | regeneration | response to hydrogen peroxide | regulation of cellular process | regulation of metabolic process | hepaticobiliary system development | response to stimulus | response to stress | response to peptide | response to starvation | reproduction | response to temperature stimulus | response to molecule of bacterial origin | cellular response to toxic substance | negative regulation of metabolic process | response to nitrogen compound | response to external biotic stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | multicellular organism development | negative regulation of catalytic activity | regulation of catalytic activity | response to lipid | liver development | response to corticosteroid | response to nutrient | response to oxidative stress | acute-phase response | response to toxic substance | regulation of hydrogen peroxide metabolic process | response to bacterium | cell communication | regulation of cellular metabolic process | inflammatory response | defense response to bacterium | response to monosaccharide | multicellular organism reproduction | protein metabolic process | response to organic substance | gland development | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cellular oxidant detoxification | negative regulation of hydrogen peroxide metabolic process | positive regulation of cell death | organic substance metabolic process | response to vitamin | animal organ development | response to reactive oxygen species | response to heat | serine-type endopeptidase activity | serine-type peptidase activity | response to L-ascorbic acid | negative regulation of molecular function | signaling | regulation of oxidoreductase activity | response to organic cyclic compound | endopeptidase activity | response to biotic stimulus | developmental process | spermatogenesis | regulation of reactive oxygen species metabolic process | detoxification | negative regulation of oxidoreductase activity | response to organonitrogen compound | response to electrical stimulus | response to lead ion | acute inflammatory response | immune system process | peptidase activity | regulation of cell death | response to carbohydrate | response to steroid hormone | aging | sexual reproduction | response to ionizing radiation | response to other organism | negative regulation of reactive oxygen species metabolic process | signal transduction | animal organ regeneration | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | haptoglobin-hemoglobin complex | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | protein-containing complex | endomembrane system | extracellular region | membrane-bounded organelle | organelle | extracellular space | blood microparticle | intracellular
