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AKT
NextBio Summary
General Info
Curated Studies
Most Correlated Studies
T helper D10 cells time course TCR activation in the presence of Akt inhibition
CD8-positive melanoma-infiltrating lymphocytes treated with AKT inhibitor VIII (AKTi-1-2)
Breast adenocarcinoma MCF7 and colon carcinoma HCT116 cells treated w/ small molecule AKT inhibitor
PDK1 null and Akt inhibitor treated cytotoxic T-lymphocyte expression data
Akt transfected regulatory T cells treated with TGFbeta
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Most Relevant Literature
Exendin-4 induces myocardial protection through MKK3 and Akt-1 in infarcted hearts.
Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression.
Osthole Protects Bone Marrow-Derived Neural Stem Cells from Oxidative Damage through PI3K/Akt-1 Path…
Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth.
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
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Clinical Trials
Most Relevant Clinical Trials
Autonomic Phenotype Before and After Akt Inhibition
Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma
Akt Inhibitor MK2206 in Treating Patients With Progressive, Recurrent, or Metastatic Adenoid Cyst Ca…
Safety, Pharmacokinetics (PK) of AKT and MEK Combination
Akt Inhibitor MK2206 in Treating Patients With Advanced Gastric or Gastroesophageal Junction Cancer
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