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AZD5438
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
ID4
XIST
WIF1
STEAP1
CRIP1
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
organic cyclic compound binding
cytosol
heterocyclic compound binding
cell periphery
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Repurposing AZD5438 and Dabrafenib for Cisplatin-Induced AKI.
AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects …
Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunoru…
AZD5438-PROTAC: A selective CDK2 degrader that protects against cisplatin- and noise-induced hearing…
Restricted suitability of BODIPY for caging in biological applications based on singlet oxygen gener…
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Clinical Trials
Most Relevant Clinical Trials
AZD5438 in Patients With Advanced Solid Malignancies
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