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Brachyury
(compound)
Summary
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Epiblastic stem cells sorted T/brachyuri positive or negative and treated with chiron
Clival chordoma UM-Chor1 cells with transcription factor T knockdown
Embryo caudal ends with mesoderm specific SRF knockout
Presomitic mesoderm tissue from mice transgenic for dominant-negative CREB (A-CREB)
Clival chordoma UM-Chor1 cells treated with THZ1 or actinomycin D
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Literature
Most Relevant Literature
An intact brachyury function is necessary to prevent spurious axial development in Xenopus laevis.
Expression of brachyury in hemangioblastoma: potential use in differential diagnosis.
T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal …
Activin A promotes hematopoietic fated mesoderm development through upregulation of brachyury in hum…
Spermatogonial stem cell self-renewal requires ETV5-mediated downstream activation of Brachyury in m…
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Clinical Trials
Most Relevant Clinical Trials
Cancer Vaccine Targeting Brachyury Protein in Tumors
Safety and Tolerability Trial (MVA-BN-Brachyury/FPV-Brachyury)
BN Brachyury and Radiation in Chordoma
Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (Qu…
Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachy…
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