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CAL-101
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Summary
General Info
Genetic Markers
Most Correlated Genes
MAL
XIST
DHRS2
CRIP1
AGR2
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
cytosol
organic cyclic compound binding
heterocyclic compound binding
cell periphery
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Curated Studies
Most Correlated Studies
B cell nascent RNA after treatment with PI3K inhibitors idelalisib or duvelisib
Diffuse large B-cell lymphoma TMD8 cells resistant to PI3K-delta inhibitor idelalisib
L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
CAL-101: a phosphatidylinositol-3-kinase p110-delta inhibitor for the treatment of lymphoid malignan…
Combined Treatment with PI3K Inhibitors BYL-719 and CAL-101 Is a Promising Antiproliferative Strateg…
PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic.
CAL-101,a novel agent of targeted therapy in hematological malignancies].
Synergistic suppression of the PI3K inhibitor CAL-101 with bortezomib on mantle cell lymphoma growth…
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Clinical Trials
Most Relevant Clinical Trials
Sequential Regimen of Bendamustine-Debulking Followed by CAL-101 and GA101-Induction and -Maintenanc…
Study to Investigate Effects of CAL-101 in Subjects With Allergic Rhinitis Exposed to Allergen in an…
Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies
An Extension Study for Subjects Who Are Deriving Benefit With Idelalisib (GS-1101; CAL-101) Followin…
Safety and Efficacy Study of Idelalisib (GS-1101, CAL-101) in Patients With Previously Treated Low-g…
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