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CDK4
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Fetal lung
Uterus
Peritoneum
Ovary
Microglial cell
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Disease Atlas
Most Correlated Diseases
Disease due to Orthopoxvirus
Injury of heart
Disease caused by parasite
Disease due to Adenovirus
Injury of eye region
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Pharmaco Atlas
Most Correlated Compounds
5-(6)-carboxyfluorescein diacetate succinimidyl ester
ITF 2357
NQ Y15
pyroxamide
sodium bisulfide
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Knockdown Atlas
Most Correlated Gene Perturbations
mir-124
Ahr
CLN5
CDK4
MIR103A2
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Diagnostic and management challenges for MDM2-, CDK4-negative fatty tumors of the retroperitoneum.
CDK4/RB/E2Fs axis as potential therapeutic target of endometrial cancer.
A refractory case of CDK4-amplified spinal astrocytoma achieving complete response upon treatment wi…
Development of Selective Cyclin-Dependent Kinase 4 Inhibitors for Antineoplastic Therapies.
The DNA deaminase APOBEC3B interacts with the cell-cycle protein CDK4 and disrupts CDK4-mediated nuc…
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Clinical Trials
Most Relevant Clinical Trials
To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer
LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE)
A Trail of CDK4 / 6 Inhibitor and MEK Inhibitor in the Treatment of Metastatic Digestive System Tumo…
Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Enc…
Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced…
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