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CDK6 protein
Summary
General Info
Curated Studies
Most Correlated Studies
HeLa cells after G0-G1 / G1-S arrest release with CDK4/6 shRNA and IL-1a treated
Breast cancer MCF-7 cells with Abemaciclib and SR11302
Granulocyte-monocyte progenitors treated with cyclosporine A (CsA) or FK506
Acute myeloid leukemia MV4-11 cells treated with BSJ-03-123, YKL-06-102 and palbociclib
Breast cancer MCF7 cells ER+ with acquired fulvestrant resistance
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Literature
Most Relevant Literature
Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthino…
Targeting CDK6 in hormone receptor-positive breast cancer: inhibitor discovery for precision oncolog…
Unveiling Conformational States of CDK6 Caused by Binding of Vcyclin Protein and Inhibitor by Combin…
CDK6 inhibits de novo lipogenesis in white adipose tissues but not in the liver.
CDK6 protein expression is associated with disease progression and treatment resistance in multiple …
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Clinical Trials
Most Relevant Clinical Trials
Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Enc…
Testing Palbociclib (PD-0332991) as Potentially Targeting Treatment in Cancers With CDK4 or CDK6 Amp…
Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Pati…
Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia
Testing Palbociclib (PD-0332991) as a Potential Targeted Treatment in Cancers With CCND1, 2, 3 Ampli…
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