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QuickView for Combretastatin A-4 (compound)


Genetic Markers

Most Correlated Genes

  1. HBB
  2. COL11A1
  3. CADM1
  4. NTRK2
  5. XIST
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Pathway Enrichment

Most Correlated Biogroups

  1. cytosol
  2. organic cyclic compound binding
  3. regulation of nitrogen compound metabolic process
  4. heterocyclic compound binding
  5. organic cyclic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature

Most Relevant Literature

  1. Hypoxia-activated glutamine antagonist prodrug combined with combretastatin A4 nanoparticles for tum…
  2. Nanoparticles Composed of PEGylated Alternating Copolymer-Combretastatin A4 Conjugate for Cancer The…
  3. Implantable Sandwich-like Scaffold/Fiber Composite Spatiotemporally Releasing Combretastatin A4 and …
  4. Combretastatin A4-derived payloads for antibody-drug conjugates.
  5. Pegylated liposomal encapsulation improves the antitumor efficacy of combretastatin A4 in murine 4T1…
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Clinical Trials

Most Relevant Clinical Trials

  1. Safety and Effectiveness of Combretastatin A-4 Phosphate Combined With Chemotherapy in Advanced Soli…
  2. Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degeneration
  3. Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascula…
  4. Combretastatin A4 Phosphate in Treating Patients With Advanced Anaplastic Thyroid Cancer
  5. Study of Combretastatin and Paclitaxel/Carboplatin in the Treatment of Anaplastic Thyroid Cancer
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