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QuickView for DNMT1 (gene)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. Hematopoietic stem cell of bone marrow
  3. Natural killer cell of peripheral blood
  4. Thymus gland
  5. T Lymphocyte (CD4+) of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Sensorineural hearing loss
  2. Cerebellar ataxia
  3. Sleep disorder
  4. Bacterial pneumonia
  5. Sepsis due to coagulase negative Staphylococcus
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Pharmaco Atlas

Most Correlated Compounds

  1. torsemide
  2. Ciprofloxacin
  3. Amlodipine
  4. Citalopram
  5. sparfloxacin
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. hsa-miR-365a-3p
  2. FUBP3
  3. PRPH2
  4. ATXN3
  5. BP1
Explore Knockdown Atlas Results

Curated Studies

Most Correlated Studies

  1. DNA Methyltransferase, Dnmt1, for the Development and Function of Foxp3+ Treg cells
  2. Colorectal cancer HCT116 and DKO1 cells treated with 5-aza-CdR or SAHA
  3. Embryonic carcinoma NCCIT cell line with DNMTs siRNA knockdown
  4. Embryonic stem cells with DNMT1/DNMT3a/DNMT3b triple knockout and/or HP1a/HP1b/HP1g depletion
  5. Colon tumors from DNA hypomethylated APCmin mice with DNMT1 hypomorphic mutation and DNMT1 knockout
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Literature

Most Relevant Literature

  1. DNMT1 Y495C mutation interferes with maintenance methylation of imprinting control regions.
  2. Loss of Claudin-1 incurred by DNMT aberration promotes pancreatic cancer progression.
  3. Unveiling the impact of DNA methylation machinery: Dnmt1 and Dnmt3a in orchestrating oocyte developm…
  4. DNMT1 methylation of LncRNA-ANRIL causes myocardial fibrosis pyroptosis by interfering with the NLRP…
  5. Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity.
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Clinical Trials

Most Relevant Clinical Trials

  1. Immunohistochemical Evaluation of DNA Methylation and Histone Modification in H. Pylori Associated G…
  2. p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic Cancer
  3. Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Ca…
  4. Azacitidine and Lintuzumab in Treating Patients With Previously Untreated Myelodysplastic Syndromes
  5. NTX-301 in MDS/AML
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