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DNMT3A protein
Summary
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Curated Studies
Most Correlated Studies
Breast cancer MCF-7 cells with doxycycline-induced ZF-DNMT3A fusion protein expression
Embryonic stem cells with DNMT1/DNMT3a/DNMT3b triple knockout and/or HP1a/HP1b/HP1g depletion
Embryonic J1 stem cells with DNMT1 DNMT3A DNMT3B triple KO expressing wildtype or mutant DNMT3A2
Embryonic stem and primordial germ cells derived and maintained in different culture conditions
Liver gene expression in Trim28 heterozygous mutant mice
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Literature
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Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer.
Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration.
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and h…
DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to d…
MiR-532-3p inhibited the methylation of SOCS2 to suppress the progression of PC by targeting DNMT3A.
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Clinical Trials
Most Relevant Clinical Trials
Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Pa…
5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors
Clinical Research for Azacitidine Combined With Low-dose Dasatinib in Maintenance Therapy of Acute M…
Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia
MIF Involvement in AML
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